Scientific poster title: "iLite® cell-based assays – A good fit to evaluate the most critical parameters included in the clinical bioassay characterization iLite® hCG case study"
In this scientific poster, we showcase that iLite hCG Assay Ready Cells can be used for the quantification of hCG activity, or neutralizing antibody response against hCG in test samples, including human serum.
Ferring has used iLite cells and their proprietary drug/API to develop bioanalytical assays determining the most critical parameters monitored during drug development:
• Serum tolerance
• Cut-point determination
• NAb assay sensitivity
• Drug tolerance at high level of drug
The iLite technology can be adapted for many applications throughout the drug development phases including drug manufacturing processes such as the quantification of vector potency and functionality or the detection of neutralizing anti-drug antibodies (NAb).