"Characterization of a Reporter Gene Cell Line for the Easy Assessment of Therapeutic AAV Vectors – A Case Study"
Poster written by Jordi Rodó - Research Scientist, Karin Blume - Taam Lead & Senior Scientist, and Therese Segerstein - Product Manager.
Learn more about the development of a reporter gene assay technology, that allows assessment and quantification of presence, activity, and function of a therapeutic AAV vector.
"Quantification of the Neutralizing Antibody Response to Recombinant AAV Vectors - Highly sensitive iLite® reporter assay, providing a highly sensitive, rapid, precise method for quantifying NAb response to a wide range of recombinant AAV vectors.”
Speaker: Michael G. Tovey, Ph.D. - Chief Scientific Advisor of Svar Life Science, France. (Track: Immunogenicity Assessment and Management)
Learn about an assay based on a packaging cell line expressing a recombinant virus, containing a tag sequence within the ITRs and a serotype-specific cap gene recognized specifically by a reporter cell line stably transfected with a luciferase reporter-gene placed under the control of an AAV-responsive chimeric promoter.