Autoimmunity

Supporting autoimmune-related projects and studies

Svar offer a portfolio of analytical parameters for the diagnosis of autoimmune diseases with highly sensitive and established technologies.

With a recognized track record of developing innovative tests, now used in everyday clinical practise, Svar is a pioneer and ground-breaker in autoimmune diagnostics. 

With diagnostic laboratory services specialized in the field of autoimmunity that analyze and measure an increasing number of autoantibodies employing a broad spectrum of techniques, Svar supports autoimmune-related projects and studies.

Our Bioanalytical Services offer a range of services for non-clinical as well as clinical studies for pharma, biotech, and CRO customers.

Applications

The recently developed iLite® reporter gene assay technology offers accurate monitoring of drug potency and detection of neutralizing antibodies (NAbs) during treatment of autoimmune diseases with biologics.

The iLite® reporter gene assay technology provides a flexible solution during the whole drug development continuum, answering the increasing demand of biological and targeted drug therapies in the Global Autoimmune Drug Market.

Several of the immunoassays provided by Svar are valuable during the development of new potential drugs within the field of autoimmunity. 

Looking for information on autoimmune disease diagnostics?

Want to know more about our autoimmunity solutions and how they help diagnosticians and researchers in their investigations to reach an accurate diagnosis faster?

Our comprehensive autoimmunity portfolio offers analytical parameters for the diagnosis of autoimmune diseases and broad spectrum of techniques and methods to support autoimmune-related projects and studies.
 
Svar is a pioneer and ground-breaker in autoimmune diagnostics with innovative tests, now used in everyday clinical practise.

Product Portfolio - General Autoimmunity

What causes autoimmune disorders?

Autoimmunity is formally defined as an immune response leading to reaction with self-antigen, i.e. any molecule that is a normal body constituent. Clinically, autoimmunity is a condition where the immune system fails to recognize its own cells and tissues as “self”. Instead, immune responses are launched against these cells and tissues as if they were foreign or invading bodies. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. 

There are more than 100 human diseases currently classified as autoimmune. Autoimmune diseases may affect a particular organ or tissue or have a systemic manifestation. The most common diseases are psoriasis, Grave's disease, rheumatoid arthritis (RA) and thyroiditis. Others, like Goodpasture syndrome, are very rare. Women are more affected than men and, in diseases like lupus, 85% of patients are females.

Diagnosis of a particular autoimmune disease can be challenging. However, the development of specific serological tests for the presence of particular autoantibodies has improved and accelerated accurate diagnosis. Early diagnosis is of significant importance as several effective drugs are available.

The Immune System

The immune system is a biological defence system against foreign harmful pathogens. The first line of defence is the innate system which provides an immediate but unspecific response.

This system is composed of different set of white blood cells, immunomodulating small molecules and complement. If the pathogen evades the innate response the second line of response, the adaptive immune system is activated. There is a close cross-talk between the innate and adaptive immune system.

The adaptive system uses different components such as T/B cells and antibodies and in this phase the immune system adapt its response during an infection to improve its recognition of the pathogen.

The Immune System

The immune system is a biological defence system against foreign harmful pathogens. The first line of defence is the innate system which provides an immediate but unspecific response.

This system is composed of different set of white blood cells, immunomodulating small molecules and complement. If the pathogen evades the innate response the second line of response, the adaptive immune system is activated. There is a close cross-talk between the innate and adaptive immune system.

The adaptive system uses different components such as T/B cells and antibodies and in this phase the immune system adapt its response during an infection to improve its recognition of the pathogen.