The Wieslab® PR3-ANCA test kit is an ELISA for detection and quantitation of IgG antibodies to proteinase 3 (PR3) in human sera.
The assay is used to detect antibodies in a single serum specimen and the results of the assay are to be used as an aid to the diagnosis of granulomatosis with polyangiitis (Wegener’s granulomatosis).
Approximately 80-90% of patients with Wegener’s granulomatosis manifest PR3-ANCA. PR3-ANCA also occurs in other systemic vasculitides, e.g. microscopic polyangiitis and focal and extracapillary necrotizing glomerulonephritis.
Product code | PR3 IU |
Assay target | PR3-ANCA |
Size | 96 wells |
Technology | ELISA |
Read-out of results | Quantitative, |
Range | 0-200 IU/mL |
Assay time | 2h |
Detection system | ALP/pNPP read at 405 nm |
Regulatory status | IVD, CE labeled |
All reagents in the kit are ready for use except wash solution and should be stored at 2-8° C.
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