INDIVIDUAL TEST 403, 404, 405, 406

Phosphatidylserine antibodies

  • 404 Phosphatidylserine IgA
  • 405 Phosphatidylserine IgG
  • 403 Phosphatidylserine IgGAM screen
  • 406 Phosphatidylserine IgM

IndicationIf suspicion of antiphospholipid syndrome (APS) remains despite negative results regarding the classical antiphospholipid associated antibodies (lupus anticoagulant (LA), IgG- and/or IgM-antibodies against beta2-Glycoprotein-1 and cardiolipin), IgA-antibodies against cardiolipin/ beta2-Glycoprotein-1 support the APS-diagnosis in isolated cases. In addition, antibodies against phosphatidylserine can be of value.MethodELISA
Can be tested as IgGAM or as individual IgG/IgA/IgM.AnswerThe result is given as negative or positive with a value (U/ml)InterpretationAutoantibodies against phosphatidylserine are associated with antiphospholipid syndrome (APS) which is characterized by arterial and venous thromboses and by recurrent miscarriages.

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Autoimmune diagnostics

ENSKILD ANALYS 403, 404, 405, 406

Fosfatidylserin antikroppar

  • 404 Phosphatidylserine IgA
  • 405 Phosphatidylserine IgG
  • 403 Phosphatidylserine IgGAM screen
  • 406 Phosphatidylserine IgM

IndikationOm misstanke på antifosfolipidsyndrom (APS) kvarstår vid negativt resultat för lupus antikoagulans, IgG- och/eller IgM-antikroppar mot anti-beta2-Glykoprotein-1 och/eller kardiolipin rekommenderas att analysera antikroppar av IgA-klass mot beta2-Glykoprotein-1 och kardiolipin, som har rapporterats förekomma i enstaka fall. Även antikroppar mot fosfatidylserin kan vara av värde.MetodELISA
Kan testas som IgGAM eller som enskilda IgA/IgG/IgM.SvarResultatet anges som negativt eller positivt med värde (U/ml).TolkningAutoantikroppar mot fosfatidylserin är associerade med antifosfolipidsyndrom (APS) som kännetecknas av ökad trombosbenägenhet (arteriella och venösa tromboser) och upprepade missfall.

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Autoimmun diagnostik