INDIVIDUAL TEST 403, 404, 405, 406
Phosphatidylserine antibodies
- 404 Phosphatidylserine IgA
- 405 Phosphatidylserine IgG
- 403 Phosphatidylserine IgGAM screen
- 406 Phosphatidylserine IgM
Indication
If suspicion of antiphospholipid syndrome (APS) remains despite negative results regarding the classical antiphospholipid associated antibodies (lupus anticoagulant (LA), IgG- and/or IgM-antibodies against beta2-Glycoprotein-1 and cardiolipin), IgA-antibodies against cardiolipin/ beta2-Glycoprotein-1 support the APS-diagnosis in isolated cases. In addition, antibodies against phosphatidylserine can be of value.
Method
ELISA
Can be tested as IgGAM or as individual IgG/IgA/IgM.
Answer
The result is given as negative or positive with a value (U/ml)
Interpretation
Autoantibodies against phosphatidylserine are associated with antiphospholipid syndrome (APS) which is characterized by arterial and venous thromboses and by recurrent miscarriages.
Can't find what you're looking for? We are here to help
ENSKILD ANALYS 403, 404, 405, 406
Fosfatidylserin antikroppar
- 404 Phosphatidylserine IgA
- 405 Phosphatidylserine IgG
- 403 Phosphatidylserine IgGAM screen
- 406 Phosphatidylserine IgM
Indikation
Om misstanke på antifosfolipidsyndrom (APS) kvarstår vid negativt resultat för lupus antikoagulans, IgG- och/eller IgM-antikroppar mot anti-beta2-Glykoprotein-1 och/eller kardiolipin rekommenderas att analysera antikroppar av IgA-klass mot beta2-Glykoprotein-1 och kardiolipin, som har rapporterats förekomma i enstaka fall. Även antikroppar mot fosfatidylserin kan vara av värde.
Metod
ELISA
Kan testas som IgGAM eller som enskilda IgA/IgG/IgM.
Svar
Resultatet anges som negativt eller positivt med värde (U/ml).
Tolkning
Autoantikroppar mot fosfatidylserin är associerade med antifosfolipidsyndrom (APS) som kännetecknas av ökad trombosbenägenhet (arteriella och venösa tromboser) och upprepade missfall.