We are currently looking for new users to try our iLite cell-based reporter gene assays. Find out how they can help in your bioassay and analytical work packages
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iLite Functional Bioassays are based on a reporter gene system that offers a convenient and powerful way of measuring and quantifying drug potency, detecting NAbs, and assessing immunogenicity.
Receptors, specific for a certain target or ligand, are expressed on the surface of a cell. Once a ligand binds to the receptor, an intracellular signaling cascade is triggered, which activates a luciferase reporter gene.
Bioassays using reproducible cell lines are essential components of the analytical package. Functional bioassays based on luminescence are known to be very robust, delivering high sensitivity and a wide dynamic range. An additional advantage of iLite cells is that they are delivered in an assay-ready format for superior ease of use.
This format gives the assay a rapid turnaround time – all iLite assays are performed within a workday or at most overnight.
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