In a recent interview by Select Science, Dr. Marie-Agnès Dragon-Durey highlights the role of complement C4d and calprotectin in the detection, diagnosis, and treatment of viral infectious diseases.
The complement system is an important part of the innate immune response and plays a key role in the defense against invading pathogens, including viruses, bacteria, fungi, and parasites. Recent studies have shown that complement overactivation plays a critical role in the pathogenesis of COVID-19 and other viral diseases, suggesting its huge potential as a biomarker for infectious diseases.