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Functional and biomarker assays for the exploration of every angle of the complement system
Our cell-based bioassays are based on iLite® technology – a cleverly designed cell-based assay system with reporter gene readouts
AAV Neutralizing Antibody (NAb), Total Antibody (TAb), and Complement Activation assays designed to provide a comprehensive view of vector immunogenicity
Solutions for detecting and semi-quantitating IgG antibodies against CCP
Our extensive CRO Services offer bioanalysis, biomarker discovery, and GMP QC testing.
With over 30 years of experience in autoimmune diagnostics, our ISO15189-certified specialist laboratory can help you reach the correct diagnosis. We also provide testing services and support for therapeutic drug monitoring.
Let us develop a custom iLite® cell line tailored to your needs.
Our cell services are highly reliable and innovative, tailored to your manufacturing needs
Many development programs struggle with maintaining consistent ADA assay performance over time - especially when overly-stringent acceptance criteria or evolving study conditions increase the risk of assay failures.
This poster highlights practical strategies to safeguard robustness and ensure reliable immunogenicity monitoring throughout long‑term studies.
Key insights include:
How optimized LPC design and acceptance ranges can prevent avoidable assay rejections
Why balanced cut‑point calculations reduce false positives while reflecting true population variability
The value of continuous data trending for early detection of performance shifts
Approaches to refining acceptance criteria using more representative datasets
Download the poster to learn more about creating resilient, clinically relevant ADA assays.