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Biomarker Discovery Services

We Care About the Quality of Your Data

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We Care About the Quality of Your Data

Biomarker Discovery Services

Svar Life Science delivers innovative solutions for your therapeutic development. Leveraging 30+ years of immunoassay expertise and advanced technologies, we offer protein biomarker discovery services to identify novel drug targets early in development. Our exploratory approach helps uncover biomarkers that monitor disease progression, predict treatment response, and assess toxicity, accelerating the path to life-saving therapies.

Our Biomarker Discovery offering

We leverage our expertise to ensure the accuracy and reliability of your data analysis, and accelerate your biomarker discovery program.

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We offer the following services in a non-GxP setting:

  • Expert help with assay setup
  • Assay optimization
  • Sample analysis
  • Quality control of data
  • Data reporting

Biomarker discovery platforms

Biomarker discovery
MSD®-ECL Biomarker Discovery
Biomarker discovery
Olink® PEA technology
Biomarker discovery
Simoa® technology

MSD®-ECL Biomarker Discovery 

Leveraging the Meso Scale Discovery (MSD) electrochemiluminescence (ECL) platform, we deliver sensitive, precise, and scalable assays—built fit for purpose and aligned to your context of use. From single markers to complex multiplex panels, our MSD solutions generate reliable data in challenging matrices to keep your programs moving.

Why teams choose our MSD®-ECL service

  • More signal, less background: ECL detection provides high sensitivity and broad dynamic range with excellent precision—ideal for clinical sample variability.
  • Multiplex at scale: Measure up to 10 analytes per well in 96 well MULTI SPOT plates (or up to 4 in 384 well format) to conserve sample and increase throughput.
  • Extensive menu & customization: Access >600 assays and >300 U PLEX analytes, or build tailored panels matched to your study endpoints.
  • Ultrasensitive when needed: S PLEX® achieves fg/mL detection for very low abundance biomarkers, available in singleplex and multiplex formats.

What we deliver

MSD-ECL
Customized Development
Fit for purpose assay development aligned to your context of use (exploratory, qualified, or validated), with platform selection and method design tailored to your matrices and endpoints.  
MSD-ECL
Flexible Testing
Single marker and multiplex biomarker testing (including discovery panels up to 50 plex) for PK/PD, safety, and translational research.
MSD-ECL
End to end support
Sample testing, data analysis and reporting, designed for decision-readiness across preclinical and clinical phases.  
MSD-ECL
Platform capacity
With two fully operational MSD instruments we can meet the demands of any project, enabling efficient turnaround times for both small scale studies and high volume projects. 

High Quality Proteomics - Olink® PEA technology

Utilizing the unique Proximity Extension Assay (PEA) technology from Olink®, we offer ideal broad screening-to-targeted discovery solutions.  

 


Target 96

Designed Panels with Relative Quantification

  • Simultaneous analysis of 92 protein biomarkers
  • Broad library of over 1100 established or exploratory protein biomarkers
  • Uses only 1 µL of biological sample
  • Relative quantification in NPX units
  • OLINK Target 96

    A broad selection of proteins associated with important biological functions, Cell Regulation, Development, Metabolism, and Organ Damage. See panel specifications on Olink's website

    • Olink Target 96 Organ Damage ( 92 )
      The assays in this panel include proteins involved in key biological processes such as response to stress, regulation of cell proliferation, cell cycle, and cell death/apoptosis.
    • Olink Target 96 Development ( 92 )
      The assays in this panel include proteins involved in key biological processes such as cell migration and motility, extracellular matrix organization, and neurogenesis.
    • Olink Target 96 Metabolism ( 92 )
      The assays in this panel include proteins involved in key biological processes such as cellular metabolic processes, cell surface receptor
      signaling pathways, regulation of phosphorylation, and cell adhesion.
    • Olink Target 96 Cell Regulation ( 92 )
      The assays in this panel include proteins involved in key biological processes such as cell communication, apoptotic process, cell cycle, and cell differentiation.
    • Olink Target 96 Mouse Exploratory ( 92 )
      The assays in this panel include proteins involved in key biological processes such as cellular regulation, development, signal transduction, and stress responses

    See panel specifications

  • OLINK Target 96

    A broad selection of proteins associated with biological functions linked to cardiovascular diseases. See panel specifications on Olink's website

    • Olink Target 96 Cardiovascular II ( 92 )
      This panel contains known human cardiovascular and inflammatory markers as well as some exploratory human proteins with great potential as new CVD markers.
    • Olink Target 96 Cardiovascular III ( 92 )
      This panel contains known human cardiovascular and inflammatory markers as well as some exploratory human proteins with great potential as new CVD markers.
    • Olink Target 96 Cardiometabolic ( 92 )
      The assays in this panel include proteins involved in key biological processes such as cellular metabolic process, cell adhesion, immune response, and complement activation.

    See panel specifications

  • OLINK Target 96

    A broad selection of proteins associated with biological functions linked to immune response and immuno-oncology diseases. See panel specifications on Olink's website

    • Olink Target 96 Immuno-Oncology ( 92 )
      The biomarkers in this panel include proteins involved in processes such as the promotion and inhibition of tumor immunity, chemotaxis, vascular and tissue remodeling, apoptosis and cell killing, and metabolism and autophagy.
    • Olink Target 96 Immune Response ( 92 )
      The assays in this panel include proteins involved in key biological processes such as adaptive immune response, defense response to viruses, lymphocyte activation, inflammatory response, and cytokine-mediated signaling pathways.

    See panel specifications

  • OLINK Target 96

    A broad selection of proteins associated with inflammatory and immune response processes.  See panel specifications on Olink's website

    Olink Target 96 Inflammation ( 92 )

    • This represents the most extensive panel available on the market for proteins associated with inflammatory diseases and related biological processes, enabling the investigation of protein signatures with high efficiency and robustness and accelerating the speed of finding new and relevant human protein biomarkers related to inflammation.

    See panel specifications

  • OLINK Target 96

    A broad selection of proteins associated with neurological functions and associated diseases. See panel specifications on Olink's website

    • Olink Target 96 Neuro Exploratory ( 92 )
      The assays in this panel include a combination of exploratory and established markers with a focus on neurology-related diseases and biological processes such as axon development, neurogenesis, and synapse assembly. The established proteins include Neurofilament light polypeptide (
      Uniprot no. P07196)*, which is an important marker for degenerative neurological diseases and traumatic brain injury.

    • Olink Target 96 Neurology ( 92 )
      The assays in this panel offer a mix of established markers related to neurobiological processes and neurological diseases (e.g. neural development, axon guidance, synaptic function, or specific conditions such as Alzheimer’s disease), as well as some more exploratory proteins with broader roles in processes such as cellular regulation, immunology, development, and metabolism. Of the 92 assays provided, 89 are unique to this panel.

    See panel specifications

  • OLINK Target 96

    A broad selection of proteins associated with biological functions linked to the initiation and progression of cancer, such as angiogenesis, cell communication, cellular metabolic processes, apoptosis, cell proliferation/differentiation, etc. See panel specifications on Olink's website

    • Olink Target 96 Oncology II ( 92 )
      The panel comprises 92 putative cancer-related human proteins that participate in biological mechanisms that are central to the initiation and progression of cancer, e.g. angiogenesis, cell-cell signaling, cell-cycle control, and inflammation. 
    • Olink Target 96 Oncology III ( 92 )
      The panel comprises 92 human proteins that participate in biological mechanisms that are central to the initiation and progression of cancer, e.g. angiogenesis, cell communication, cellular metabolic processes, apoptosis, cell proliferation/differentiation, etc. This panel perfectly complements the Olink® Target 96 Oncology II panel, enabling the measurement of 184 proteins in 2 dedicated panels.

    See panel specifications


Target 48

Designed Panels with Absolute and Relative Quantification

  • Allow for simultaneous analysis of 45 protein biomarkers
  • Uses only 1 µL of biological sample
  • Results reported in standard concentration units (pg/mL) or relative quantification (NPX units)
  • OLINK Target 48

    A solution for cytokine studies and inflammation-related diseases, offering a broad selection of proteins associated with biological functions linked to inflammation - the most important proteins covering key pathways related to cytokine signaling and inflammatory processes are well covered. See panel specifications on Olink's website

    • Olink Target 48 Cytokine ( 45 )
      Olink’s Target 48 Cytokine panel is the high-performance solution for cytokine studies and inflammation-related diseases, with absolute or relative quantification. The thorough selection of biomarkers ensures that the most important proteins covering key pathways related to cytokine signaling and inflammatory processes are well covered.

    See panel specifications

  • OLINK Target 48
    Olink’s Target 48 Immune Surveillance is a carefully designed and thoroughly validated panel containing 44 immune-related proteins. This panel can be combined and processed simultaneously with the Olink Target 48 Cytokine panel for a more comprehensive analysis of immune mediators.

    See panel specifications

  • OLINK Target 48
    Olink Target 48 Mouse Cytokine Panel is the high-performance solution for in-depth view of cytokine signaling and inflammatory pathways for pre-clinical and translational research. It can be utilized across key application areas to deepen current understanding of molecular pathways involved in the disease initiation and progression.

    See panel specifications

  • OLINK Target 48

    The Target 48 Neurodegeneration is a critical tool that enables the detection and quantification of key and emerging neurodegenerative disease biomarkers from plasma and cerebrospinal fluid samples. By generating quantitative data, it ensures reproducible results across and within longitudinal studies, moving a step forward towards clinical utilization.

    See panel specifications


Olink Flex

Designed Panels with flexibility in mind:

  • Allow for the combination of ~ 200 protein biomarkers
  • Results reported in standard concentration units (pg/mL) or relative quantification (NPX units)
  • Simultaneous analysis of 5-30 protein biomarkers
OLINK Flex
Olink Flex

Olink Focus

Customized panels:

  • Broad library of over 5000 protein biomarkers
  • Customized panels for specific and exclusive studies
  • Results reported in standard concentration units (pg/mL) or relative quantification (NPX units)
  • Simultaneous analysis of 21 protein biomarkers
OLINK Focus
Olink Focus

Ultra-sensitive detection - Simoa® technology

Utilizing high-quality single-molecule arrays (Simoa®) technology, we can support your exploratory biomarker detection in a variety of biological matrices with a sensitivity in the femtomolar range, well below the detection limit of the best ELISAs.

Simoa assays are available in the following therapeutic areas: COVID-19, neurology, oncology, immunology, cardiology, and infectious diseases.

In addition, utilizing our 30 years of assay development experience, we can support you in developing high-quality Simoa-based assays for your specific needs.

 

 

Key applications using SIMOA

SIMOA APPLICATION
Enhanced drug target selection
Biomarkers can provide insights into the biological pathways involved in a disease, which can help researchers identify potential drug targets.
SIMOA APPLICATION
Establishment of better biofluid biomarkers
Biomarkers can be measured in a matrix of liquid biosamples, increasing accessibility and recurrence, and convenience of sampling.
SIMOA APPLICATION
Indication of drug mechanism of action
A deep understanding of disease biology provides insights into the mechanism of drug action.
SIMOA APPLICATION
Monitoring drug response
By analyzing biomarkers, researchers can monitor and potentially predict how patients will respond to different treatments, allowing for more personalized and effective therapies.

Maximize Your Sample Analysis with Our Expert Optimization

Our Biomarker Discovery Services provide exceptional support that helps maximize your sample analysis. Our team of experts is committed to providing you with expert optimization that meets your needs. We use cutting-edge technologies to make sure that you get accurate results that are reliable and reproducible.

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