Access a complete portfolio of complement ELISAs, biomarker panels, and functional assays to evaluate complement pathways and support safety and efficacy studies.
Complement System Evaluation
Complement System Evaluation
The complement system is central to innate immunity, influencing inflammation, immune regulation, and disease progression, making its evaluation essential for therapeutic development.
How we can help
We provide comprehensive solutions for evaluating complement system activity and its role in immune response. From pathway-specific ELISAs to functional assays and biomarker analysis, our offerings help you generate reliable data for safety and efficacy studies.
Our complement solutions can be used for:
- Safety Assessment: Detects complement activation that may lead to adverse reactions in biologics and medical devices.
- Mechanism of Action Studies: Confirms therapeutic impact on immune pathways and device interactions.
- Regulatory Compliance: Provides data required for biologics, gene therapy, and medical device submissions.
Our Complement System Evaluation Solutions
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COMPLEMENT ASSAYS
WIESLAB® ELISAs quantify classical, alternative, and lectin pathway activation with clear, pathway‑resolved outputs. Assay‑ready kits reduce setup time and are ideal for safety studies, comparability, and mechanism-of-action (MoA) investigations.
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CRO SERVICES
We measure complement components and activation fragments to map immune dynamics over time. Panels are configurable and validated for reproducibility, enabling cross‑study comparisons.
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COMPLEMENT ASSAYS
Cell‑based and reporter assays capture complement‑mediated effects such as opsonization and lysis. Delivered with reference controls and standard curves, they support potency, safety, and mechanistic studies.
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WIESLAB DIAGNOSTIC SERVICES
We offer diagnostic test panels for complement deficiency, complement function, and complement activation. In addition, we offer testing for individual complement components.
FAQ
What is complement system evaluation?
Complement system evaluation involves assessing complement activity, complement activation, and complement-related biomarkers to better understand immune system function.
How is complement activity measured?
Complement activity is commonly assessed using functional assays that evaluate the classical, alternative, or lectin pathways.
Why is complement activation important?
Complement activation plays a significant role in immune defense, inflammation, drug development, autoimmune diseases, and other biological processes.
Which complement pathways can be evaluated?
Researchers can evaluate the classical pathway, alternative pathway, and lectin pathway individually or together depending on study objectives.
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