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Follow the Complement Path

We have decades of experience in developing complement system assays. Our experienced scientists work closely with key opinion leaders to create sensitive, reliable, and user-friendly products, covering all aspects of the complement system.

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Follow the Complement Path

Complement System Solutions

Svar has decades of experience in designing products for studying the complement system. Our complement experts have created assays that let you study any part of the complement system – from individual complement components and the amplification loop to all three complement system pathways. Just follow the complement path.

Complement Solutions

We offer complement assays in convenient ELISA and iLite® cell-based reporter gene formats. Regardless of what format you select, you will get:

  • Reliable, objective, and easy-to-interpret results
  • Results in just a few hours
  • Low inter-assay variability and excellent reproducibility
  • Ready-to-use reagents for a streamlined workflow
  • Excellent specificity
  • Lower batch-to-batch variation & faster results than hemolytic methods

Our Complement Products

FILTER VIEW
ALL ELISA Cell-Based Biomarker Complement Pathway IVD
AAV9COMPLRUO

AAV9-induced Complement Activation ELISA

Evaluate and characterize complement activation induced by Adeno-Associated Virus 9 (AAV9) vectors

ELISA
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Complement system | AAV Complement Activation Assays | AAV9COMPLRUO | AAV | Complement | ELISA | Immunoassay HRP/TMB read at 450 nm | Research Use Only |
COMPL C4d RUO

Complement C4d

Detect complement activation via the classical and lectin pathways with this C4d biomarker sandwich ELISA

ELISA
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Complement system | Biomarker Assays | COMPL C4d RUO | ELISA | Immunoassay HRP/TMB read at 450 nm | Classical pathway | Research Use Only |
COMPL FPF RUO

Complement Factor P Functional Assay

Zoom in on the amplification loop of the alternative complement pathway with this Factor P functional ELISA

ELISA
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Complement system | Functional Assays | COMPL FPF RUO | ELISA | Immunoassay HRP/TMB read at 450 nm | Research Use Only |
BM4073

iLite® C3a Assay Ready Cells

Quantitative measurement of complement C3a activity in a cell-based format

CELL-BASED
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Cell-based reporter gene bioassay | Functional Bioassays | BM4073 | Luciferase Reporter Assay | Complement | Cell-based reporter gene assay | Luminescence | Complement Products | Research Use Only |
BM4075

iLite® C5a Assay Ready Cells

Quantitative measurement of complement C5a activity in a cell-based format

CELL-BASED
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Cell-based reporter gene bioassay | Functional Bioassays | BM4075 | Luciferase Reporter Assay | Complement | Cell-based reporter gene assay | Luminescence | Complement Products | Research Use Only |
BM5028

iLite® CD20 (+) Svar Luc Assay Ready Cells

Designed for sensitive and reproducible assessment of CDC activity

CELL-BASED
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Cell-based reporter gene bioassay | CDC Bioassays | BM5028 | CDC | Complement | Cell-based reporter gene assay | Luminescence | Complement Products | Research Use Only |
COMPLAP330

WIESLAB® Complement Alternative Pathway (IVD)

Analyze specific activation of the alternative pathway with this functional ELISA

ELISA
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Complement system | Functional Assays | COMPLAP330 | ELISA | Immunoassay ALP/pNPP read at 405 nm | IVD, CE labeled |
COMPLAP330RUO

WIESLAB® Complement Alternative Pathway (RUO)

Research-use-only ELISA for profiling alternative complement pathway activation

ELISA
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Complement system | Functional Assays | COMPLAP330RUO | ELISA | Immunoassay ALP/pNPP read at 405 nm | Research Use Only |
COMPLCP310

WIESLAB® Complement Classical Pathway (IVD)

Quantify the activation of the classical complement pathway

ELISA
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Complement system | Functional Assays | COMPLCP310 | ELISA | Immunoassay ALP/pNPP read at 405 nm | IVD, CE labeled |
COMPLCP310RUO

WIESLAB® Complement Classical Pathway (RUO)

Sensitive analysis of classical pathway activation

ELISA
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Complement system | Functional Assays | COMPLCP310RUO | ELISA | Immunoassay ALP/pNPP read at 405 nm | Research Use Only |
COMPLMP320

WIESLAB® Complement MBL Pathway (IVD)

Explore the activation of the lectin complement pathway

ELISA
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Complement system | Functional Assays | COMPLMP320 | ELISA | Immunoassay ALP/pNPP read at 405 nm | IVD, CE labeled |
COMPLMP320RUO

WIESLAB® Complement MBL Pathway (RUO)

RUO ELISA for pathway-specific detection of MBL-mediated complement activation

ELISA
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Complement system | Functional Assays | COMPLMP320RUO | ELISA | Immunoassay ALP/pNPP read at 405 nm | Research Use Only |
COMPL300

WIESLAB® Complement Screen (IVD)

Gain a complete picture of complement activation across all three pathways

ELISA
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Complement system | Functional Assays | COMPL300 | ELISA | Immunoassay ALP/pNPP read at 405 nm | IVD, CE labeled |
COMPL300RUO

WIESLAB® Complement Screen (RUO)

A RUO-format screening assay that evaluates activation of the classical, lectin, and alternative pathways

ELISA
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Complement system | Functional Assays | COMPL300RUO | ELISA | Immunoassay ALP/pNPP read at 405 nm | Research Use Only |

Didn't find what you were looking for?

We offer products customized to your needs. Our custom iLite® reporter-gene assays can be adapted to almost any target. We also offer custom ELISA plates and other products. In addition, you can take advantage of our service offerings and let us do the work for you.

Complement News

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Advancing Safer AAV Gene Therapies Through Comprehensive Immunogenicity Assessment

Advancing Safer AAV Gene Therapies Through Comprehensive Immunogenicity Assessment

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The Increasingly Central Role of The Complement System AAV-induced Immune Reaction

The Increasingly Central Role of The Complement System AAV-induced Immune Reaction

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Discover Svar AAV Immunogenicity Suite

Discover Svar AAV Immunogenicity Suite

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New AAV9-induced Complement Activation Assay

New AAV9-induced Complement Activation Assay

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NEW SPECIALIST REVIEW: Complement System

NEW SPECIALIST REVIEW: Complement System

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Introducing the AAV Complement Activation Assay

Introducing the AAV Complement Activation Assay

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Introducing the new iLite® C3a Assay Ready Cells

Introducing the new iLite® C3a Assay Ready Cells

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Celebrating 20 Years of the Wieslab Complement System Assays

Celebrating 20 Years of the Wieslab Complement System Assays

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Targeting the Complement System: A New Era in Disease Treatment

Targeting the Complement System: A New Era in Disease Treatment

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Driving Discovery: 600+ Studies Featuring Our Products

Driving Discovery: 600+ Studies Featuring Our Products

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Gearing Up for the Future: Navigating IVDR Compliance

Gearing Up for the Future: Navigating IVDR Compliance

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Advancements in Complement System Therapeutics

Advancements in Complement System Therapeutics

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Wieslab Functional Complement & CCP Kit

Wieslab Functional Complement & CCP Kit

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next

Complement Downloads

previous
Complement System Specialist Review

Complement System Specialist Review

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Get a Free Complement System Poster

Get a Free Complement System Poster

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A Guide to Complement Therapeutics for Drug Development Professionals

A Guide to Complement Therapeutics for Drug Development Professionals

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Investigating the multiple roles of C5a and its receptors in diseases and pregnancy

Investigating the multiple roles of C5a and its receptors in diseases and pregnancy

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Crossing Barriers: Unraveling the role of complement in neurodegenerative diseases

Crossing Barriers: Unraveling the role of complement in neurodegenerative diseases

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Novel COVID-19 Biomarkers: The role of complement C4d

Novel COVID-19 Biomarkers: The role of complement C4d

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Riding the Wave: the Complement Revolution in Neurodegeneration Research

Riding the Wave: the Complement Revolution in Neurodegeneration Research

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Unraveling Complement’s Role in Blindness: The Work of Professor Simon Clark

Unraveling Complement’s Role in Blindness: The Work of Professor Simon Clark

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Translating Research into Care - Exploring Complement with Dr Sophie Chauvet

Translating Research into Care - Exploring Complement with Dr Sophie Chauvet

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Insights on Targeting Complement Dysregulation - Dr. Elena Goicoechea de Jorge

Insights on Targeting Complement Dysregulation - Dr. Elena Goicoechea de Jorge

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How to Perform a Wieslab® Complement System Screen

How to Perform a Wieslab® Complement System Screen

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20 Years of Innovation: The Legacy of the WIESLAB® Complement System Assays

20 Years of Innovation: The Legacy of the WIESLAB® Complement System Assays

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Developing a Customizable Complement-Dependent Cytotoxicity Assay

Developing a Customizable Complement-Dependent Cytotoxicity Assay

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Meet the 2025 Svar Complement Excellence Award Recipients

Meet the 2025 Svar Complement Excellence Award Recipients

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Insights from Two Complement Excellence Award Recipients

Insights from Two Complement Excellence Award Recipients

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next

20+
years of product development

All 3
complement pathways studied individually

<5h
assay time

265+
scientific paper references

FAQ

How do I choose the right complement assay?

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The choice depends on whether you want to study complement activation, complement function, individual complement biomarkers, or cell-based complement responses.

What complement pathways can be studied using Svar's assays?

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Svar offers assays for the classical, alternative, and lectin complement pathways as well as assays targeting individual complement components and activation products.

What is the difference between complement activation and complement function assays?

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Complement functional assays measure how effectively a complement pathway is working, while complement activation assays measure biomarkers generated when the complement system has been activated.

Do you offer both ELISA and cell-based complement assays?

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Yes. The portfolio includes both ELISA assays and iLite cell-based reporter assays for complement research.

Which complement biomarkers can be measured?

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Assays are available for biomarkers such as, C3a, C5a, C4d, TCC, Factor P (Properdin) and other complement-related assays.

Can these assays be used in drug development?

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Yes. The assays support complement research across basic research, translational studies and drug development.

How can I identify the best assay for my research project?

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Researchers can browse products by application area or contact Svar's complement specialists for guidance

Do you offer RUO and IVD complement assays?

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Yes. Several of our complement assays are available in both RUO and IVD formats, depending on the intended application and local regulatory requirements.

Contact our complement team

Write us a message and a complement specialist will get in touch