Let us guide you on
the Complement Path

Complement System Solutions

At a glance

We offer functional and biomarker assays that can be used to explore every angle of complement system-involvement in a wide range of application areas.

  • Reliable, objective and easy-to-interpret results
  • Results in just 3 hours – from days to hours compared to competing technologies
  • Low inter-assay variability and excellent reproducibility
  • Based on the well-established and flexible ELISA technology
  • Developed by our in-house experts in collaboration with key opinion leaders
  • Ready-to-use reagents for a streamlined workflow
  • Excellent specificity means clear results without false positives
  • Only company to offer exploration of all three complement system pathways individually

Complement Therapeutics Video - Thumbnail

Movie: Let us guide you on the complement path

We have long experience and a proven track-record

The complement system is an integral part of the innate immune response. Given its important role in many human disorders, complement activation studies are important in a wide range of applications – from drug development and medical device safety to clinical diagnostics and basic research.

Svar has over 15 years’ experience of complement system assay development. Our complement system assays have been developed by our experienced scientists in close collaboration with key opinion leaders, to yield sensitive, reliable and easy-to-use products for the exploration of most aspects of the complement system.


Reliable, objective and easy-to-interpret results in just 3 hours

Based on the well-established and robust ELISA technology, our products can be used in standard setups as well as automated setups with ELISA robots. Ready-to-use reagents contribute to the ease-of-use of the assays.

Svar’s complement activity biomarker assays offer excellent specificity, which means that you get easy-to-interpret data without having to worry about false positives. In addition, our assays offer low batch-to-batch variation compared to hemolytic methods – where erythrocytes can differ between lots – which means more consistent and robust results.

Taken together, you can get reliable and objective results in just 3 hours ­­– from days to hours compared to hemolytic assays.

Four main product categories

Our complement portfolio is divided into the following categories:

Biomarker assays

Ideal for detection of complement activation or dysregulation in the complement system.

Functional assays

Perform analyses of all three pathways to get the full picture of the complement system.

Cell-based assays

iLite® cell-based functional reporter-gene assay in an assay-ready format. Enables a fast, streamlined work process with low variability.

Flexi Solutions

Complement products for your flexible assay setup on automated platforms of your choice.

Complement Product Portfolio

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Get a free complement system poster

Register to receive your free poster showing the complement system pathways.
 
 
complement-poster
 

Complement system review paper

Learn about the complement system, clinical manifestations, regulation, complement tests, therapeutic monitoring and more.
 
 
complement-paper
 

Learn about some common applications of our Complement Assays

Read our top 3 reasons to study the complement system

Find out about the benefits of using our Complement Assays

HOW DOES THE COMPLEMENT SYSTEM WORK?

The complement system is a complex system composed of a large number of proteins that act in a sequential cascade. 

The complement system consists of three different pathways called the classical, lectin and alternative pathways. The activation of each pathway is triggered by different mechanisms/components.
 
 
 

Did you know that all our complement assays are available through our Laboratory Services for research projects in drug development and as clinical routine testing?

Our Bioanalytical Services can make a difference in your drug development project.

They offer:

  • validation of drug targets and batch release
  • evaluation of off-target reactions
  • development of treatment algorithms and monitoring regimens