iLite the way
We have extensive experience developing cell-based reporter-gene assays using our proprietary iLite technology. These assays are ideal for quantifying drug potency, detecting NAbs, and assessing biologically relevant functionality in biopharmaceutical development.
iLite the way
Luciferase Reporter Assays
Svar’s functional cell-based bioassays use our proprietary iLite® technology, a cleverly engineered system with target-induced reporter gene readout. They offer ease of use and robustness and can be developed for virtually any pharmaceutical target. Most of our cell-based reporter-gene assays come with a secondary reporter gene that acts as an internal control, compensating for differences in cell number and matrix effects.
iLite Cell-Based Reporter Gene Assays
We offer iLite cell-based reporter gene assays for a wide range of targets or custom-made for your target of choice. Regardless of what assay you select, you will get:
- High sensitivity and large dynamic range
- "Assay-ready" format for rapid and convenient use
- Reproducible and biologically relevant results
- Reduced assay variability and higher reproducibility compared to cells in culture
Our Luciferase Reporter Assays
FILTER VIEWiLite® IL-23 Assay Ready Cells
Precise measurement of IL-23-induced signaling in a cell-based context
iLite® TNF-alpha Assay Ready Cells
Reproducible, cell-based quantification of TNF-α bioactivity. Ideal for functional testing of anti-TNF therapeutics and mechanism-of-action studies
iLite® C5a Assay Ready Cells
Quantitative measurement of complement C5a activity in a cell-based format
iLite® FGF-21 Assay Ready Cells
Cell-based measurement of FGF-21 signaling, supporting metabolic research and development of FGF-21 analogs or mimetics
iLite® G-CSF Assay Ready Cells
Reliable cell-based quantification of G-CSF activity, supporting biosimilar development and batch consistency testing
iLite® GM-CSF Assay Ready Cells
Functional quantification of granulocyte-macrophage colony-stimulating factor activity
iLite® hCG Assay Ready Cells
A sensitive, cell-based method for quantifying hCG bioactivity
iLite® IL-12 Assay Ready Cells
Functional, cell-based quantification of IL-12 signaling
iLite® IL-2 Assay Ready Cells
Sensitive quantification of IL-2 activity or inhibition
iLite® IL-6 Assay Ready Cells
Reproducible, cell-based detection of IL-6 bioactivity
iLite® Insulin Assay Ready Cells
Robust, quantitative measurement of insulin receptor activation, facilitating characterization of insulin analogs and biosimilars
iLite® RANKL Assay Ready Cells
Precise quantification of RANKL activity or blockade in a cell-based system
iLite® TLR4 Assay Ready Cells
Detection of TLR4-mediated NF-κB signaling
iLite® TLR9 Assay Ready Cells
Cell-based measurement of TLR9 pathway activation
iLite® TNF-alpha Xcel Assay Ready Cells
Pre-qualified and assay-ready, these cells provide rapid and sensitive detection of TNF-α activity
iLite® Type I IFN FAST Assay Ready Cells
Accelerated quantification of type I interferon signaling with a shortened incubation time
iLite® VEGF Assay Ready Cells
Quantification of vascular endothelial growth factor activity with high sensitivity
Didn't find what you were looking for?
We offer products customized to your needs. Our custom iLite® reporter-gene assays can be adapted to almost any target. We also offer custom ELISA plates and other products. In addition, you can take advantage of our service offerings and let us do the work for you.
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years of product development
All 3
complement pathways studied individually
<5h
assay time
265+
scientific paper references
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