Neutralizing AAV Antibody Assessment – Cell-Based Reporter Gene Assays

About

About Svar

Career

Distributors

Events

Products

All Products

Complement Assays

Cell-Based Assays

Gene Therapy Assays

CCP Assays

Services

CRO Services

Diagnostic Services

Custom Cell Development

Cell Manufacturing

Applications

Potency Testing

Safety Assessment

Biomarker Profiling

Clinical Assessment

Bioanalysis

Regulatory Testing

Complement System Evaluation

Gene & Cell Therapy Evaluation

Biosimilar & Biobetter Assessment

Knowledge

Knowledge Hub

Scientific Publications

Videos & Webinars

Product Documentation

iLite AAV NAb Assessment

Reliable Detection of Neutralizing Antibodies against AAV Capsids

Reliable Detection of AAV Neutralizing Antibodies

iLite AAV NAb Reporter Gene Assays

Our AAV NAb assessment bioassays are designed to evaluate the immunogenicity of AAV capsids for different serotypes in gene therapy. They use a two-cell line setup: an AAV-responsive reporter cell and packaging cells for the vector serotype.

Customization for any capsid – both traditional and recombinant
Packaging cells eliminate the need for vector production
Reduced incubation time for fast and high-quality results
"Assay-ready" format for rapid and convenient use
A secondary reporter gene that acts as an internal control, compensating for differences in cell number and matrix effects

BM6100

iLite^® AAV Responsive Reporter Assay Ready Cells

Reporter cell line designed to quantify AAV vector transduction efficiency and detect NAbs that impair gene delivery

CELL-BASED

BM6002

iLite^® AAV2 Packaging Assay Ready Cells

Engineered and optimized to produce AAV vectors of serotype 2 for use in NAb detection studies

CELL-BASED

BM6005

iLite^® AAV5 Packaging Assay Ready Cells

Engineered and optimized to produce AAV vectors of serotype 5 for use in NAb detection studies

CELL-BASED

BM6006

iLite^® AAV6 Packaging Assay Ready Cells

Engineered and optimized to produce AAV vectors of serotype 6 for use in NAb detection studies

CELL-BASED

BM6008

iLite^® AAV8 Packaging Assay Ready Cells

Engineered and optimized to produce AAV vectors of serotype 8 for use in NAb detection studies

CELL-BASED

BM6009

iLite^® AAV9 Packaging Assay Ready Cells

Engineered and optimized to produce AAV vectors of serotype 9 for use in NAb detection studies

CELL-BASED

Your Target of Choice

We can create bioassays for your vector. Our CRO Services also offer this as a service.

Didn't find what you were looking for?

We offer products customized to your needs. Our custom iLite^® reporter-gene assays can be adapted to almost any target. We also offer custom ELISA plates and other products. In addition, you can take advantage of our service offerings and let us do the work for you.