DIAGNOSTIC TEST 080

Agrin Antibodies

Diagnostic test for antibodies against Agrin. For suspicion of myasthenia gravis.

Indication

Suspicion of Myasthenia Gravis (MG)

Sample material

Serum

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Cell-based assay (CBA), indirect immunofluorescence (IIF)

Reference interval

<1:10 negative

Result

Results are reported as negative or positive with titer.

Interpretation

Autoantibodies against Agrin have been reported to occur in 2-15% of patients with Myasthenia Gravis (MG) but the diagnostic and prognostic value is however unclear.

References

  • Lazaridis K, Tzartos SJ. Front Immunol. 2020. Autoantibody Specificities in Myasthenia Gravis; Implications for Improved Diagnostics and Therapeutics. PMID 32117321
  • Koneczny I, Herbst R. Cells. 2019. Myasthenia Gravis: Pathogenic Effects of Autoantibodies on Neuromuscular Architecture. PMID: 31269763
  • Fichtner ML et al. Int Rev Neurobiol. 2025. Autoantibodies in myasthenia gravis. PMID: 40675742

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-10-09