DIAGNOSTIC TEST PANEL 541

Drug Induced Lupus

Diagnostic test panel for ANA (HEp-2) and antibodies against histones. For suspicion of drug-induced lupus or vasculitis.

Indication

Suspicion of drug-induced lupus or vasculitis.

Clinical background

Through various mechanisms, some drugs may give lupus-like syndromes as a side effect. They may activate a latent lupus or cause a separate syndrome called drug-induced lupus. The symptom comprises a constellation of systemic symptoms like fever, myalgia, arthritis, and rashes. Renal effects and CNS symptoms are unusual. Differences and similarities between drug-induced lupus and spontaneous lupus are shown in the table below. The medicines that are mainly associated with drug-induced lupus are procainamide, hydralazine, diltiazem, and anti-TNF (tumor necrosis factor) preparations.

Patients with renal complications often have necrotizing glomerulonephritis that may be associated with P-ANCA, where the antibodies are usually directed against MPO or lactoferrine.

Organ symptoms in SLE and drug-induced lupus.

Tests included in panel

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How to order

This test panel is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.
  2. Prepare your samples

    Serum: At least 1 mL serum (plain serum tubes without additives).
  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Samples can be sent at room temperature to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-08-18