DIAGNOSTIC TEST PANEL 541
Drug Induced Lupus
Diagnostic test panel for ANA (HEp-2) and antibodies against histones. For suspicion of drug-induced lupus or vasculitis.
Indication
Suspicion of drug-induced lupus or vasculitis.
Clinical background
Through various mechanisms, some drugs may give lupus-like syndromes as a side effect. They may activate a latent lupus or cause a separate syndrome called drug-induced lupus. The symptom comprises a constellation of systemic symptoms like fever, myalgia, arthritis, and rashes. Renal effects and CNS symptoms are unusual. Differences and similarities between drug-induced lupus and spontaneous lupus are shown in the table below. The medicines that are mainly associated with drug-induced lupus are procainamide, hydralazine, diltiazem, and anti-TNF (tumor necrosis factor) preparations.
Patients with renal complications often have necrotizing glomerulonephritis that may be associated with P-ANCA, where the antibodies are usually directed against MPO or lactoferrine.
Organ symptoms in SLE and drug-induced lupus.
Tests included in panel
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How to order
This test panel is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 1 mL serum (plain serum tubes without additives).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Samples can be sent at room temperature to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-08-18