DIAGNOSTIC TEST 095

HSP-70 Antibodies

Diagnostic test for antibodies against HSP-70. For suspicion of autoimmune hearing loss.

Note: We are currently experiencing delivery delays for the HSP-70 antibody reagent kit; therefore, the reporting turnaround time is expected to be prolonged. We will resume testing as soon as the reagent kit becomes available (expected in September 2026).

Indication

Suspicion of autoimmune hearing loss

Sample material

Serum

  • Minim. volume: 0.5 mL

Transport

Within Sweden

  • room temperature

International

  • cold

Method

Immunoblot

Reference interval

Negative

Result

Results are reported as negative or positive.

Interpretation

Antibodies against HSP-70 have been reported to occur in up to 40% of patients with idiopathic hearing loss, but the clinical value is unclear.

References

  • Yamanobe S, Harris JP. Laryngoscope. 1993. Inner ear-specific autoantibodies. PMID: 7680088
  • Shin SO et al. Laryngoscope. 1997. Comparison of anti-heat shock protein 70 (anti-hsp70) and anti-68-kDa inner ear protein in the sera of patients with Meniere's disease. PMID: 9023247
  • Moscicki RA et al. JAMA. 1994. Serum antibody to inner ear proteins in patients with progressive hearing loss. Correlation with disease activity and response to corticosteroid treatment. PMID: 8057517
  • Hirose K et al. Laryngoscope. 1999. Utility of laboratory testing in autoimmune inner ear disease. PMID: 10569401

Included in these panels

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. If you are a new customer, please also include a completed customer information form.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Last updated: 2026-08-10