INDIVIDUAL TEST 613
Eculizumab
Indication
Monitoring of Eculizumab level
Sample material
Serum
- Minim. volume: 0,7 mL
Transport
- Within Sweden: cold
- International: cold
Method
- ELISA
Result
Drug concentration is reported as µg/mL.
Interpretation
Eculizumab acts as a complement inhibitor through preventing the complement protein C5 to be cleaved. The sample should be drawn at trough value. Low or unmeasurable concentration of the biologic pharmaceutical is associated with poor clinical effect.
Last updated: 2025-06-02
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ENSKILD ANALYS 613
Eculizumab
Indikation
Monitorering av Eculizumab-koncentration
Provmaterial
Serum
- Minim. volym: 0,7 mL
Transport
- Inom Sverige: kylt
- Internationellt: kylt
Metod
- ELISA
Resultat
Läkemedelskoncentrationen anges i µg/mL.
Tolkning
Eculizumab verkar som komplementhämmare genom att förhindra att komplementproteinet C5 klyvs. Provet bör tas vid dalvärde. Låg eller omätbar koncentration av biologiskt läkemedel är associerat med sämre klinisk effekt.
Senast uppdaterat: 2025-06-02