DIAGNOSTIC TEST 856
ITPR1 Antibodies (IgG)
Diagnostic test for antibodies against ITPR1. For suspicion of autoimmune encephalitis /autoimmune cerebellar ataxia.
Indication
Suspicion of autoimmune encephalitis or autoimmune cerebellar ataxia
Sample material
Serum
- Minim. volume: 0,5 mL
CSF
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Cell-based assay (CBA), indirect immunofluorescence (IIF)
Reference interval
Serum: <1:100 negative
CSF: negative
Result
Results are reported as negative or positive. A positive result is followed by a titer (serum).
Interpretation
Autoantibodies against ITPR1 are reported in autoimmune cerebellar ataxia and sub-acute neuropathy, other neurological manifestations can occur. Association with malignancy has been reported.
References
- Cirkel A et al. Neurol Res Pract. 2021. Paraneoplastic encephalomyeloradiculits with multiple autoantibodies against ITPR-1, GFAP and MOG: case report and literature review. PMID: 34635185
- Jarius S et al. J Neuroinflammation. 2022. Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature. PMID: 35907972
Included in these panels
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How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
CSF: At least 0.5 mL CSF (polypropylene tubes).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-12-01
