DIAGNOSTIC TEST 986
Neurogranin
Diagnostic test for Neurogranin. For Alzheimer's disease, memory examination.
Indication
Suspicion of Alzheimer's disease and in memory examination
Sample material
CSF
- Minim. volume: 0,5 mL
Transport
- Within Sweden: frozen
- International: frozen
Method
ELISA
Reference interval
<245 ng/L normal
Result
Results are reported as normal or elevated with a concentration (ng/L).
Interpretation
Neurogranin is a postsynaptic protein that is important for memory function and is expressed in areas damaged by Alzheimer’s disease. Elevated levels can be seen in the early stages and are higher in Alzheimer's disease compared to other neurodegenerative diseases.
References
- Agnello L et al. Diagnostics (Basel). 2021. Neurogranin as a Reliable Biomarker for Synaptic Dysfunction in Alzheimer's Disease. PMID: 34943576
- Richter G et al. Neurobiol Aging. 2025. Comparison of CSF neurofilament light chain and total tau as neurodegeneration markers: Associations with synaptic markers and cognitive outcomes. PMID: 40669105
- Das S et al. Alzheimer's Res Ther. 2024. The use of synaptic biomarkers in cerebrospinal fluid to differentiate behavioral variant of frontotemporal dementia from primary psychiatric disorders and Alzheimer's disease. PMID: 38355535
Included in these panels
Need pricing information?
How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
CSF: At least 0.5 mL CSF (polypropylene tubes).
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Send samples and request form
Within Sweden
Send samples frozen to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples frozen to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-12-01
