INDIVIDUAL TEST 900
C3
Indication
Suspicion of complement activation or other deviations within the complement system
Sample material
EDTA-plasma
- Minim. volume: 0,5 mL
Transport
- Within Sweden: frozen
- International: frozen
Method
Nephelometry
Reference interval
0.67-1.29 g/L
Result
Results are reported as as normal, low, or elevated with a concentration (g/L).
Interpretation
Elevated level of C3 can be seen in acute phase reaction.
Complementary analyses are often required for the assessment.
References
- Andrulli S et al. Front Immunol. 2025. Isolated C3 hypocomplementemia as an early predictor of chronic kidney disease in lupus nephritis. PMID: 41019087
- Ishchenko A et al. RMD Open. 2025. Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein. PMID: 40992787
Last updated: 2025-12-05
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ENSKILD ANALYS 900
C3
Indikation
Komplementaktivering eller andra avvikelser inom komplementsystemet
Provmaterial
EDTA-plasma
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: fryst
- Internationellt: fryst
Metod
Nefelometri
Referensintervall
0.67-1.29 g/L
Resultat
Resultat anges som normalt, sänkt eller förhöjt med koncentration (g/L).
Tolkning
Förhöjd nivå C3 kan ses vid akutfasreaktion.
Kompletterande analyser krävs ofta för bedömningen.
Referenser
- Andrulli S et al. Front Immunol. 2025. Isolated C3 hypocomplementemia as an early predictor of chronic kidney disease in lupus nephritis. PMID: 41019087
- Ishchenko A et al. RMD Open. 2025. Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein. PMID: 40992787
Senast uppdaterat: 2025-12-05