INDIVIDUAL TEST 926
C1 INH Function
Indication
Investigation of angioedema
Method
The analysis is performed on plasma with spectrophotometry.
Result
The result is reported as a percentage of normal human serum and as normal or reduced. Reference interval: 72-129 %.
Interpretation
Results below the lower reference limit may indicate hereditary angioedema (HAE) type 1 or consumption of C1-inhibitor (can be seen in some malignancies). The result should primarily be verified with a new sample as well as to include analysis of concentration of C1-inhibitor and C4.
References
- Li HH et al; COMPACT Investigators. Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled randomized study. Allergy Asthma Clin Immunol. 2019 15:49. PMID: 31485239.
Last updated: 2024-06-18
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ENSKILD ANALYS 926
C1-INH funktion
Indikation
Vid utredning av angioödem
Metod
Analysen utförs på plasma med spektrofotometri.
Resultat
Resultatet anges som procent av normalt humanserum och som normalt eller sänkt. Referensintervall: 72-129%.
Tolkning
Resultat under nedre referensgränsen kan tyda på hereditärt angioödem (HAE) typ 1 eller konsumtion av C1-inhibitor (kan ses vid vissa maligniteter). Resultatet bör i första hand verifieras med nytt prov för verifiering och även inkludera analys av koncentration av C1-inhibitor och C4.
Referenser
- Li HH et al; COMPACT Investigators. Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled randomized study. Allergy Asthma Clin Immunol. 2019 15:49. PMID: 31485239.
Senast uppdaterat: 2024-06-18