DIAGNOSTIC TEST PANEL 571
Hereditary Angioedema (HAE)
Diagnostic test panel for C4, C1-INH level, and C1 INH function. For investigation of angioedema and chronic urticaria.
Indication
Investigation of angioedema and in chronic urticaria.
Clinical background
Hereditary angioedema (HAE) is an autosomal dominant disease caused by low levels of the plasma protein C1 inhibitor (C1-INH).
Deficiencies in C1-INH allow unchecked activation of the classic complement pathway and other biochemical systems. Patients can present with any combination of painless, nonpruritic, nonpitting swelling of the skin (cutaneous angioedema), severe abdominal pain, or acute airway obstruction.
There are 3 types of HAE. Type I HAE is defined by low plasma levels of a normal C1-INH protein. Type II HAE is characterized by the presence of normal or elevated levels of a dysfunctional C1-INH. Type III HAE has been recently identified as an estrogen-dependent inherited form of angioedema occurring mainly in women with normal functional and quantitative levels of C1-INH.
Tests included in panel
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How to order
This test panel is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
EDTA Plasma: At least 0.5 mL blood plasma (EDTA tubes).
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Send samples and request form
Within Sweden
Send samples frozen to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples frozen to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-08-18
