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iLite® Metabolic Panel

As metabolic therapeutics become increasingly sophisticated, researchers need reliable tools to evaluate biological activity across multiple pathways. The iLite® Metabolic Panel brings together key metabolic targets, enabling consistent functional assessment.

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Fueling the Development of Next-Generation Metabolic Therapeutics

Metabolic Target Assays

The metabolic therapeutics landscape is evolving rapidly. New generations of obesity and diabetes treatments increasingly combine multiple mechanisms of action to achieve improved efficacy and patient outcomes. As therapeutic strategies become more advanced, teams need practical tools that can help them generate biologically relevant functional data faster.

The iLite® Metabolic Panel is a suite of assay-ready reporter gene assays designed to deliver biologically relevant functional data across key metabolic targets. The panel brings together key targets within a single reporter gene assay platform, enabling consistent functional assessment from discovery through development.

Built on a common cell engineering and reporter technology platform, the iLite Metabolic Panel enables direct comparison of activity across individual metabolic pathways while maintaining consistency in assay design, performance, and workflow.

Whether developing single-target agonists, dual agonists, or next-generation multi-target therapeutics, developers gain access to a scalable platform that supports confident decision-making throughout the development lifecycle.

Our Metabolic Assays Solutions

BM3071

iLite® FGF-21 Assay Ready Cells

Cell-based measurement of FGF-21 signaling, supporting metabolic research and development of FGF-21 analogs or mimetics

CELL-BASED
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Cell-based reporter gene bioassay | Functional Bioassays | BM3071 | Luciferase Reporter Assay | Metabolic | Cell-based reporter gene assay | Luminescence | Growth Factors |
BM4110

iLite® GIP Assay Ready Cells

This iLite® GIP reporter assay provides cell-based functional studies of GIP and its receptor GIPR, supporting metabolic research and development of incretin-based therapeutics.

CELL-BASED
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Cell-based reporter gene bioassay | Functional Bioassays | BM4110 | Luciferase Reporter Assay | Metabolic | Cell-based reporter gene assay | Luminescence |
BM4100

iLite® GLP-1 Assay Ready Cells

This iLite® GLP-1 reporter assay provides cell-based functional studies of GLP-1 and its receptor GLP1R, supporting metabolic research and development of incretin-based single- and multi-agonist therapeutics.

CELL-BASED
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Cell-based reporter gene bioassay | Functional Bioassays | BM4100 | Luciferase Reporter Assay | Metabolic | Cell-based reporter gene assay | Luminescence |
BM3060

iLite® Insulin Assay Ready Cells

Robust, quantitative measurement of insulin receptor activation, facilitating characterization of insulin analogs and biosimilars

CELL-BASED
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Cell-based reporter gene bioassay | Functional Bioassays | BM3060 | Luciferase Reporter Assay | Metabolic | Cell-based reporter gene assay | Luminescence | Hormones |

Didn't find what you were looking for?

We offer products customized to your needs. Our custom iLite® reporter-gene assays can be adapted to almost any target. We also offer custom ELISA plates and other products. In addition, you can take advantage of our service offerings and let us do the work for you.

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One Platform. Multiple Pathways. Faster Development Decisions.

Built on Svar Life Science's proprietary iLite® dual-reporter technology, the Metabolic Panel provides a unified approach to functional characterization and potency assessment across metabolic drug programs.

Tailored for the development of next-generation therapeutics

Confident decision-making

driven by data that reflect the true biological function

Deeper mechanistic insights

through MoA-reflective functional reporter assays

Direct side-by-side comparison

of candidates and modalities through a unified engineered cell system with built-in normalization

Precise potency assessment

with high sensitivity and a broad dynamic range

High assay reproducibility and low variability

optimal for QC testing, validation and tech transfer

Robust immunogenicity testing

with high serum tolerance

Faster time-to-results with the assay ready cells format

The iLite® Assay Ready Cells format removes the complexity of routine cell culture, reducing workflow complexity compared with conventional cell-based assay approaches.

Developers can progress from thawing to readout within the same day, minimizing hands-on time while improving assay consistency across sites, studies, and development stages.

iLite flow diagram

 

iLite News

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Translating Complex Metabolic Biology into Functional Insight

Translating Complex Metabolic Biology into Functional Insight

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Introducing the iLite® Metabolic Panel

Introducing the iLite® Metabolic Panel

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Introducing the new iLite® C3a Assay Ready Cells

Introducing the new iLite® C3a Assay Ready Cells

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Improved Speed and Accuracy in Immunogenicity Testing

Improved Speed and Accuracy in Immunogenicity Testing

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Transitioning to Second-Generation iLite Cells

Transitioning to Second-Generation iLite Cells

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iLite Downloads

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Systematic Analysis of Fc Mutations Designed to Modulate Functional Activity

Systematic Analysis of Fc Mutations Designed to Modulate Functional Activity

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Therapeutic Antibodies Trimmed with GlycINATOR® Lose Antibody-Dependent Cell-mediated Cytotoxicity

Therapeutic Antibodies Trimmed with GlycINATOR® Lose Antibody-Dependent Cell-mediated Cytotoxicity

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Quantification of Bispecific Antibody Mediated T-cell Activation

Quantification of Bispecific Antibody Mediated T-cell Activation

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IL-6 Biology, Inhibitors & COVID-19

IL-6 Biology, Inhibitors & COVID-19

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Mechanism-linked Potency Assays Drive Gene Therapy Success

Mechanism-linked Potency Assays Drive Gene Therapy Success

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Addressing the Analytical Gaps in Modern Therapeutic Development

Addressing the Analytical Gaps in Modern Therapeutic Development

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Developing a Customizable Complement-Dependent Cytotoxicity Assay

Developing a Customizable Complement-Dependent Cytotoxicity Assay

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Partnering for Success in a New Era of Advanced Therapeutics

Partnering for Success in a New Era of Advanced Therapeutics

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The Immune Response to AAV Gene Therapy

The Immune Response to AAV Gene Therapy

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How to Design Potency Assays for Gene Therapy Projects

How to Design Potency Assays for Gene Therapy Projects

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A Cell-Based ADCC Bioassay Comparison

A Cell-Based ADCC Bioassay Comparison

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Quantification of the Neutralizing Antibody Response to Recombinant AAV Vectors

Quantification of the Neutralizing Antibody Response to Recombinant AAV Vectors

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Svar Complement Assays: Analyzing How Drug Candidates Affect the Complement System

Svar Complement Assays: Analyzing How Drug Candidates Affect the Complement System

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Assay Development in AAV Therapies: Engineering iLite® Cell Lines for Specific and Analytical Applications

Assay Development in AAV Therapies: Engineering iLite® Cell Lines for Specific and Analytical Applic...

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Measuring C5a With a Functional Bioassay

Measuring C5a With a Functional Bioassay

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