As metabolic therapeutics become increasingly sophisticated, researchers need reliable tools to evaluate biological activity across multiple pathways. The iLite® Metabolic Panel brings together key metabolic targets, enabling consistent functional assessment.
Fueling the Development of Next-Generation Metabolic Therapeutics
Our Metabolic Assays Solutions
Didn't find what you were looking for?
We offer products customized to your needs. Our custom iLite® reporter-gene assays can be adapted to almost any target. We also offer custom ELISA plates and other products. In addition, you can take advantage of our service offerings and let us do the work for you.
Faster time-to-results with the assay ready cells format
The iLite® Assay Ready Cells format removes the complexity of routine cell culture, reducing workflow complexity compared with conventional cell-based assay approaches.
Developers can progress from thawing to readout within the same day, minimizing hands-on time while improving assay consistency across sites, studies, and development stages.
iLite News
Translating Complex Metabolic Biology into Functional Insight
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Introducing the iLite® Metabolic Panel
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Introducing the new iLite® C3a Assay Ready Cells
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Improved Speed and Accuracy in Immunogenicity Testing
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Transitioning to Second-Generation iLite Cells
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iLite Downloads
Systematic Analysis of Fc Mutations Designed to Modulate Functional Activity
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Therapeutic Antibodies Trimmed with GlycINATOR® Lose Antibody-Dependent Cell-mediated Cytotoxicity
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Quantification of Bispecific Antibody Mediated T-cell Activation
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IL-6 Biology, Inhibitors & COVID-19
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Mechanism-linked Potency Assays Drive Gene Therapy Success
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Addressing the Analytical Gaps in Modern Therapeutic Development
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Developing a Customizable Complement-Dependent Cytotoxicity Assay
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Partnering for Success in a New Era of Advanced Therapeutics
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The Immune Response to AAV Gene Therapy
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How to Design Potency Assays for Gene Therapy Projects
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A Cell-Based ADCC Bioassay Comparison
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Quantification of the Neutralizing Antibody Response to Recombinant AAV Vectors
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Svar Complement Assays: Analyzing How Drug Candidates Affect the Complement System
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Assay Development in AAV Therapies: Engineering iLite® Cell Lines for Specific and Analytical Applic...
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Measuring C5a With a Functional Bioassay
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FAQ
What are metabolic pathway assays?
Svar Life Science's iLite® Metabolic Pathway Assays are cell-based reporter gene assays designed to measure biologically relevant signaling pathways involved in metabolic regulation. They support functional studies of targets associated with obesity, diabetes, and metabolic disease research.
Which metabolic targets are available in the iLite® portfolio?
The iLite® Metabolic Panel includes assays for several key metabolic targets, including GLP-1, GIP, insulin, and FGF-21 signaling pathways.
Why use cell-based assays to study metabolic pathways?
Cell-based assays measure functional biological responses in living cells, providing insights into receptor activation and downstream signaling that are directly relevant to drug development and target characterization
What makes iLite® Metabolic Pathway Assays different?
iLite® Metabolic Pathway Assays combine a reporter gene readout with an assay-ready format, helping researchers generate reproducible and biologically relevant data while reducing assay variability and laboratory workload.
Can iLite® Metabolic Pathway Assays be used for potency testing?
Yes. These assays can support potency assessment by measuring the functional activity of metabolic drug candidates through their relevant signaling pathways.
Can iLite® assays support GLP-1 and GIP research?
Yes. iLite® assays are available for both GLP-1 and GIP signaling, enabling functional characterization of incretin-based therapeutics and related drug candidates.
Are iLite® Metabolic Pathway Assays assay-ready?
Yes. The assays are supplied in an assay-ready format, providing a convenient workflow that helps reduce preparation time and improve consistency between experiments.
Can Svar develop custom metabolic pathway assays?
Yes. Svar Life Science can develop custom iLite® reporter gene assays for specific metabolic targets, enabling tailored solutions for unique research and development programs.
