Looking to know more about immunogenicity challenges in gene therapy and the role of complement system? Dr. Anna Majowicz- Preclinical Immunology Lead at Spark Therapeutics- provides valuable insights into how investigating complement system can aid to tackle challenges in AAV-mediated gene therapy.
Read more about the potential use of complement biomarkers in managing immune responses to AAV vectors in this Editorial Article. Download yours by filling out the form.
Looking to know more about immunogenicity challenges in gene therapy and the role of complement system? Dr. Anna Majowicz- Preclinical Immunology Lead at Spark Therapeutics- provides valuable insights into how investigating complement system can aid to tackle challenges in AAV-mediated gene therapy.
Read more about the potential use of complement biomarkers in managing immune responses to AAV vectors in this Editorial Article. Download yours by filling out the form.
Providing high-quality assays for specific and quantitative determination of complement components.
AAV vectors offer great promise in delivering life-saving gene therapy but come with the challenges of adverse activation of the complement system upon administration in high doses.
Monitoring complement activation in AAV-administrated gene therapy patients is crucial to ensure the safety and durability of the gene therapy they are infused with.