Establishment of a Novel iLite^® Reporter Gene Assay Response to Insulin Products

Scientific poster title: "Establishment of a Novel iLite Reporter Gene Assay for the Quantification of the Activity and Neutralizing Antibody response to Insulin Products"

In this scientific poster, we showcase how an iLite assay responsive to insulin was developed and how assay-ready frozen iLite reporter gene cells eliminate the principal inconveniences of cell-based assays in general and provide the basis for the establishment of rapid, precise, and highly specific assays for both the quantification of human insulin activity and neutralizing anti-insulin antibodies even in the presence of human serum. 

The iLite technology can be adapted for many applications throughout the drug development phases including drug manufacturing processes such as the quantification of vector potency and functionality or the detection of neutralizing anti-drug antibodies (NAb).