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Functional and biomarker assays for the exploration of every angle of the complement system
Our cell-based bioassays are based on iLite® technology – a cleverly designed cell-based assay system with reporter gene readouts
AAV Neutralizing Antibody (NAb), Total Antibody (TAb), and Complement Activation assays designed to provide a comprehensive view of vector immunogenicity
Solutions for detecting and semi-quantitating IgG antibodies against CCP
Our extensive CRO Services offer bioanalysis, biomarker discovery, and GMP QC testing.
With over 30 years of experience in autoimmune diagnostics, our ISO15189-certified specialist laboratory can help you reach the correct diagnosis. We also provide testing services and support for therapeutic drug monitoring.
Let us develop a custom iLite® cell line tailored to your needs.
Our cell services are highly reliable and innovative, tailored to your manufacturing needs
This scientific talk, presented at PEGS 2021, presents a highly sensitive iLite® reporter assay, providing a highly sensitive, rapid, precise method for quantifying NAb response to a wide range of recombinant AAV vectors.
A highly sensitive iLite® reporter assay based on a packaging cell line expressing a recombinant virus containing a tag sequence within the ITRs and a serotype-specific cap gene recognized specifically by a reporter cell line stably transfected with a luciferase reporter-gene placed under the control of an AAV-responsive chimeric promoter will be described.