DIAGNOSTIC TEST 780
21-Hydroxylase Antibodies
Diagnostic test for antibodies against 21-Hydroxylase. For suspicion of Addison’s disease.
Indication
Suspicion of Addison’s disease
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Radioimmunoprecipitation (RIP)
Reference interval
<10 negative, 10-<15 borderline
Result
Results are reported as negative, borderline, or positive with a ratio.
Interpretation
Antibodies against Steroid 21-hydroxylase is a strong marker for autoimmune adrenal cortex insufficiency (Addison’s disease).
References
- Feyzullova A et al. J Clin Med. 2025. Prevalence of Various Systemic and Organ-Specific Autoimmune Markers in Addison's Disease Patients Compared to Healthy Controls. PMID: 40507712
- Wolff ASB et al. Front Endocrinol (Lausanne). 2023. Autoimmune primary adrenal insufficiency -current diagnostic approaches and future perspectives. PMID: 38027140
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How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-11-21
