DIAGNOSTIC TEST 850

Carbonic Anhydrase II Antibodies

Diagnostic test for antibodies against carbonic anhydrase II. Suspicion of Autoimmune Pancreatitis (type 2, AIP2).

Indication

No specific indication.

These antibodies can be found in several inflammatory conditions.

Sample material

Serum

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Western Blot

Reference interval

Negative

Result

Results are reported as negative or positive.

Interpretation

In cases of tumor-like pancreatic lesions of unknown origin, antibodies against carbonic anhydrase are associated with an autoimmune pancreatitis instead of underlying malignancy. In other cases, these antibodies are of low diagnostic value since they can be found in several inflammatory conditions.

References

  • Zamanova S et al. Expert Opin Ther Pat. 2019. Carbonic anhydrases as disease markers. PMID: 31172829
  • Kılıç H et al. Sci Rep. 2025. A case-control study on the role of carbonic anhydrase autoantibodies in the pathogenesis and diagnosis of fibromyalgia. PMID: 40240416
  • Avendaño-Monje CL et al. Ocul Immunol Inflamm. 2024. Anti-retinal Antibodies in Sarcoidosis. PMID: 36240484
  • Detlefsen S et al. Medicine (Baltimore). 2018. Value of anti-plasminogen binding peptide, anti-carbonic anhydrase II, immunoglobulin G4, and other serological markers for the differentiation of autoimmune pancreatitis and pancreatic cancer. PMID: 30075546

Included in these panels

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-11-21