DIAGNOSTIC TEST 988

CXCL13

Diagnostic test for CXCL13. For suspicion of neuroinflammation.

Indication

Suspicion of neuroborreliosis or neuroinflammation

Sample material

CSF

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: frozen
  • International: frozen

Method

ELISA

Reference interval

< 7.8 ng/L

Result

Results are reported as normal or elevated with a concentration.

Interpretation

An elevated level of the chemokine CXCL13 is seen in neuroinflammation with B-cell infiltration. A strongly elevated level is typical of neuroborreliosis. Slight to moderate increased levels can often be seen in multiple sclerosis (MS) and other neuroinflammatory diseases.

References

  • Muñoz-Sánchez G et al. Neurol Neuroimmunol Neuroinflamm. 2025. Cytokine and Chemokine Profiles in Anti-LGI1 Encephalitis: Markers of Severity and Outcome. PMID: 41115260
  • Segal Y et al. Ann Clin Transl Neurol. 2025. CSF cytokine, chemokine, and injury biomarker profile of glial fibrillary acidic protein (GFAP) autoimmunity. PMID: 39869499
  • Magliozzi R et al. Brain Pathol. 2025. Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis. PMID: 39617422

Need pricing information?

Get a quote

How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    CSF: At least 0.5 mL CSF (polypropylene tubes).

  3. Send samples and request form

    Within Sweden
    Send samples frozen to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples frozen to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-12-05