DIAGNOSTIC TEST 052
Dopamin-2 Receptor Antibodies (IgG)
Diagnostic test for antibodies against D2R. For suspicion of autoimmune encephalitis.
Indication
Suspicion of autoimmune encephalitis
Sample material
Serum
- Minim. volume: 0,5 mL
CSF
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Cell-based assay (CBA), indirect immunofluorescence (IIF)
Reference interval
Serum: <1:10 negative
CSF: negative
Result
Results are reported as negative or positive. A positive result is followed by a titer (serum).
Interpretation
Antibodies against D2R have been reported in isolated cases of autoimmune encephalitis in children.
References
- Cellucci T et al. Neurol Neuroimmunol Neuroinflamm 2020. Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient. PMID: 31953309
- Liu Y et al. Neurol Neuroimmunol Neuroinflamm. 2022. Relapsing and Immune-Responsive Paroxysmal Jaw Clonus With Blepharospasm and Sialorrhea Associated With D2R Autoantibodies. PMID: 35459715
- Gövert F et al. 2020. Neurol Res Pract. Antibody-related movement disorders - a comprehensive review of phenotype-autoantibody correlations and a guide to testing. PMID: 33324912
Included in these panels
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How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
CSF: At least 0.5 mL CSF (polypropylene tubes).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-12-05
