DIAGNOSTIC TEST 071

Endomysial Antibodies (IgA)

Diagnostic test for suspicion of celiac disease (CD) or dermatitis herpetiformis.

Indication

Suspicion of celiac disease (CD) or dermatitis herpetiformis

Sample material

Serum

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Indirect immunofluorescence (IIF)

Reference interval

Negative

Result

Results are reported as negative or positive with fluorescence intensity

Interpretation

Anti-endomysial IgA antibodies is a strong diagnostic marker for celiac disease.

Note! Determination of IgA level in serum is not included in the test. In case of IgA-deficiency, IgA-antibodies cannot be detected and analysis of antibodies of IgG-class against endomysial tissue or transglutaminase 2 is then recommended.

References

  • Lock RJ et al. J Clin Pathol. 1999. IgA anti-tissue transglutaminase as a diagnostic marker of gluten sensitive enteropathy. PMID: 10474519
  • McManus R, Kelleher D. N Engl J Med. 2003. Celiac disease--the villain unmasked? PMID: 12815145
  • Singh A et al. J Clin Med. 2019. Non-Invasive Biomarkers for Celiac Disease. PMID: 31234270
  • Al-Toma A et al. United European Gastroenterol J. 2019. European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders. PMID: 31210940

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-10-09