DIAGNOSTIC TEST 205
Envoplakin Antibodies (IgG)
Diagnostic test for antibodies against Envoplakin (IgG). For suspicion of paraneoplastic pemphigus (PNP).
Indication
Suspicion of paraneoplastic pemphigus
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
ELISA
Reference interval
<1.0 negative
Result
Results are reported as negative or positive with a ratio.
Interpretation
Anti-envoplakin (IgG) antibodies occur in PNP (paraneoplastic pemphigus) association with lymphoproliferative diseases like non-Hodgkins’s lymphoma and CLL (chronic lymphocytic leukemia). Antibody concentration correlates with disease activity and may be used to monitor treatment efficacy.
References
- Baum S et al. Autoimmun Rev. 2014. Diagnosis and classification of autoimmune blistering diseases. PMID: 24434358
- Garbanzos CCT et al. J Cutan Pathol. 2025. Clinical, Serologic, and Histopathologic Features of Patients With Pemphigus With Either Positive or Negative IgG4 Intercellular Deposition by Direct Immunofluorescence (DIF): A Retrospective Case-Control Study of 55 DIF Biopsy Specimens. PMID: 40555471
- van Beek N et al. Front Immunol. 2024. State-of-the-art diagnosis of autoimmune blistering diseases. PMID: 38903493
Included in these panels
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How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-11-21
