DIAGNOSTIC TEST 205
Envoplakin Antibodies (IgG)
Diagnostic test for antibodies against Envoplakin (IgG). For suspicion of paraneoplastic pemphigus (PNP).
Indication
Suspicion of paraneoplastic pemphigus
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
ELISA
Reference interval
<1.0 negative
Result
Results are reported as negative or positive with a ratio.
Interpretation
Anti-envoplakin (IgG) antibodies occur in PNP (paraneoplastic pemphigus) association with lymphoproliferative diseases like non-Hodgkins’s lymphoma and CLL (chronic lymphocytic leukemia). Antibody concentration correlates with disease activity and may be used to monitor treatment efficacy.
References
- Baum S et al. Autoimmun Rev. 2014. Diagnosis and classification of autoimmune blistering diseases. PMID: 24434358
- Garbanzos CCT et al. J Cutan Pathol. 2025. Clinical, Serologic, and Histopathologic Features of Patients With Pemphigus With Either Positive or Negative IgG4 Intercellular Deposition by Direct Immunofluorescence (DIF): A Retrospective Case-Control Study of 55 DIF Biopsy Specimens. PMID: 40555471
- van Beek N et al. Front Immunol. 2024. State-of-the-art diagnosis of autoimmune blistering diseases. PMID: 38903493
Included in these panels
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How to order
This test is only available as part of a test panel.
Last updated: 2026-09-14
