DIAGNOSTIC TEST 105

Erythropoietin

Diagnostic test for anti-Erythropoietin (EPO) antibodies.

Indication

Suspicion of anti-Erythropoietin (EPO) antibodies and PRCA

Sample material

Serum

  • Minim. volume: 1,0 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Radioimmunoprecipitation (RIP)

Reference interval

Negative

Result

Results are reported as negative or positive.

Interpretation

Antibodies against erythropoetin (EPO) are associated with a rare side effect in treatment with recombined human erythropoietin (RHuEPO) where anti EPO antibodies causes the development of red cell aplasia (PRCA) i.e. the lack of erythropoes.

Antikroppar mot erytropoetin (EPO) associeras med en mycket sällsynt biverkning vid behandling med rekombinant humant erytropoietin (rHuEPO) där anti-EPO antikroppar orsakar utveckling av pure red cell aplasia (PRCA) dvs. avsaknad av erytropoes.

References

  • Thorpe R, Swanson SJ. Nephrol Dial Transplant. 2005. Assays for detecting and diagnosing antibody-mediated pure red cell aplasia (PRCA): an assessment of available procedures. PMID: 15827053
  • Evens AM et al. Best Pract Res Clin Haematol. 2005. Epoetin-induced pure red-cell aplasia (PRCA): preliminary results from the research on adverse drug events and reports (RADAR) group. PMID: 15792923
  • Jelkmann W. Expert Opin Biol Ther. 2012. Biosimilar recombinant human erythropoietins ("epoetins") and future erythropoiesis-stimulating treatments. PMID: 22471247

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 1 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-12-05