DIAGNOSTIC TEST 876
GABA A Receptor Antibodies (IgG)
Diagnostic test for antibodies against GABA-AR. For suspicion of autoimmune encephalitis.
Indication
Suspicion of autoimmune encephalitis
Sample material
Serum
- Minim. volume: 0,5 mL
CSF
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- Internation: cold
Method
Cell-based assay (CBA), indirect immunofluorescence (IIF)
Reference interval
Serum: <1:10 negative
CSF: negative
Result
Results are reported as negative or positive. A positive result is followed by a titer (serum).
Interpretation
Antibodies against GABA-A receptor have been reported for autoimmune encephalitis with seizures (including status epilepticus), cognitive impairment with disorientation and hallucinations. In stiff person syndrome, these antibodies have been detected in low titers.
References
- Noviello CM et al. Cell. 2022. Structural mechanisms of GABAA receptor autoimmune encephalitis. PMID: 35803245
- Graus F et al. Neurol Neuroimmunol Neuroinflamm. 2021. Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes. PMID: 34006622
- Ryding M et al. Cells. 2023. Pathophysiological Effects of Autoantibodies in Autoimmune Encephalitides. PMID: 38201219
Included in these panels
Need pricing information?
How to order
This test is available worldwide for hospitals, clinics, and physicians.
-
Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
CSF: At least 0.5 mL CSF (polypropylene tubes).
-
Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-12-05
