DIAGNOSTIC TEST 871

Neurochondrin Antibodies (IgG)

Diagnostic test for antibodies against Neurochondrin. For suspicion of autoimmune cerebellar ataxia.

Indication

Suspicion of autoimmune cerebellar ataxia

Sample material

Serum

  • Minim. volume: 0,5 mL

CSF

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Cell-based assay (CBA), indirect immunofluorescence (IIF)

Reference interval

Serum: <1:100 negative

CSF: negative

Result

Results are reported as negative or positive. A positive result is followed by a titer (serum).

Interpretation

Antibodies against neurochondrin have been reported in cases with autoimmune cerebellar degeneration with rapidly progressive cerebellar ataxia. They are usually not associated with malignancy.

References

  • Ahmad R et al. Front Immunol. 2024. Case report: Refractory focal motor seizure associated with cerebrospinal fluid neurochondrin antibody. PMID: 39376559
  • Schwarzwald A et al. Eur J Neurol. 2023. Anti-neurochondrin antibody as a biomarker in primary autoimmune cerebellar ataxia-a case report and review of the literature. PMID: 36437687
  • Schwarzwald A et al. Eur J Neurol. 2023. Anti-neurochondrin antibody as a biomarker in primary autoimmune cerebellar ataxia-a case report and review of the literature. PMID: 36437687

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).
    CSF: At least 0.5 mL CSF (polypropylene tubes).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-12-05