DIAGNOSTIC TEST 087
Parietal Cell Antibodies
Diagnostic test for antibodies against parietal cells. For suspicion of pernicious anemia and atrophic gastritis.
Indication
Suspicion of pernicious anemia and atrophic gastritis
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Indirect immunofluorescence (IIF)
Reference interval
<1:10 negative
Result
Results are reported as negative or positive with a titer.
Interpretation
In autoimmune gastritis, antibodies against parietal cells are directed against H+K+ATPase and can lead to atrophic gastritis and pernicious anemia due to B-12 deficiency. Autoimmune gastritis is often associated with autoimmune thyroid disease.
References
- Panozzo MP et al. J Transl Autoimmun. 2025. Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function. PMID: 39917315
- Calcaterra V et al. J Endocrinol Invest. 2020. Anti-gastric parietal cell antibodies for autoimmune gastritis screening in juvenile autoimmune thyroid disease. PMID: 31264142
- Lenti MV et al. Nat Rev Dis Primers. 2020. Autoimmune gastritis. PMID: 32647173
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How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-11-21
