DIAGNOSTIC TEST 931

Properdin

Diagnostic test for Properdin. For the investigation of complement deficiency.

Indication

Suspicion of complement deficiency

Sample material

EDTA-plasma

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: frozen
  • International: frozen

Method

Addressable laser bead immunoassay (ALBIA)

Reference interval

11.4-23.1 mg/L

Result

Results in serum are given as normal, elevated or low with a concentration (mg/L).

Interpretation

By activation of the alternative pathway, properdin is consumed. Therefore, the properdin content can be used as a complement activation marker, especially in post-streptococcal nephritis and in sepsis. Hypocomplementemia with low properdin content in sepsis is a prognostically serious finding. Properdin should always be analyzed in patients with meningococcal disease.

References

  • McMurray JC et al. Allergy Asthma Proc. 2024. Immunodeficiency: Complement disorders. PMID: 39294906

Included in these panels

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    EDTA Plasma: At least 0.5 mL blood plasma (EDTA tubes).

  3. Send samples and request form

    Within Sweden
    Send samples frozen to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples frozen to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2026-01-29