DIAGNOSTIC TEST 991
pTau
Diagnostic test for pTau. For Alzheimer's disease and memory examination.
Indication
Suspicion of Alzheimer's disease or memory investigation
Sample material
CSF
- Minim. volume: 0,5 mL
Transport
- Within Sweden: frozen
- International: frozen
Method
Chemiluminescence enzyme immunoassay (CELEIA)
Reference interval
< 50 ng/L ( ≥50 years)
Result
Results are reported as a concentration (ng/L).
Interpretation
Tau is a structural protein that mostly occurs in the cortical, unmyelinated axons. Hyperphosphorylation of Tau is considered a step in the formation of Tau fibrils. Increased level of p-Tau in CSF can be seen in early stages of Alzheimer’s disease and is connected to the degree of pathological changes. The levels of p-Tau increase with the progression and severity of the disease.
References
- Jack CR Jr et al. Alzheimers Dement. 2024. Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup. PMID: 38934362
- Woyk K et al. J Alzheimers Dis Rep. 2025. The relationship of 18F-FDG-PET to other common biomarkers of dementia in a clinical cohort with memory deficits. PMID: 40290782
Included in these panels
Need pricing information?
How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
CSF: At least 0.5 mL CSF (polypropylene tubes).
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Send samples and request form
Within Sweden
Send samples frozen to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples frozen to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-12-05
