DIAGNOSTIC TEST 031

Ribosomal P-Protein (Ribo-P) Antibodies

Diagnostic test for suspicion of systemic lupus erythematosus, especially with CNS involvement.

Indication

Suspicion of systemic lupus erythematosus, especially with CNS involvement

Sample material

Serum

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

ELISA-based technique (EliA)

Reference interval

<7 U/mL negative, 7- <10 U/mL borderline

Result

Results are reported as negative, borderline, or positive with a concentration (U/mL).

Interpretation

Antibodies against Ribosomal P-protein are associated with neuropsychiatric manifestations in systemic lupus erythematosus (SLE).

References

  • Fritzler MJ et al. J Rheumatol. 2018. The Antinuclear Antibody Test in the Diagnosis of Antisynthetase Syndrome and Other Autoimmune Myopathies. PMID: 29496922
  • Pagkopoulou E et al. J Clin Med. 2025. Autoantibodies in Systemic Lupus Erythematosus: Diagnostic and Pathogenic Insights. PMID: 40869539
  • Kamstrupet S et al. Lupus Sci Med. 2025. Anti-ribosomal-P protein antibodies and systemic lupus erythematosus (SLE): in a cross-sectional study of Danish adult patients with SLE, no significant association is found between anti-ribosomal-P and neuropsychiatric SLE. PMID: 40819906

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.
  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).
  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-11-21