DIAGNOSTIC TEST 605

Ustekinumab

Diagnostic test for monitoring of Ustekinumab levels and control of Anti-Drug Antibodies (ADA) against the drug.

Indication

Monitoring of Ustekinumab level and control of Anti-Drug Antibodies (ADA) against the drug

Sample material

Serum

  • Minim. volume: 0,7 mL

Transport

  • Within Sweden: cold
  • International: cold

Method

  • Drug concentration: ELISA
  • Anti-Drug Antibodies (ADA): RIA

Result

Drug concentration is reported as µg/mL. At drug concentrations <1 μg/mL it is recommended to further test for ADA. ADA is reported as a concentration (AU/mL).

Interpretation

Ustekinumab acts as a cytokine IL-12 and IL-23 inhibitor. Low or unmeasurable concentration of the biologic pharmaceutical is associated with poor clinical effect. One explanation can be that anti-drug antibodies (ADA) block the effect and enhance clearance of the drug.

Presence of drug in the test sample may prevent the detection of ADA. To avoid this, the sample should be drawn just before the next dosing of the drug (drug trough level).

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 0.7 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Send samples cold to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-08-18