INDIVIDUAL TEST 720
Th/To Antibodies
Indication
Suspicion of scleroderma and differential diagnosis of Raynaud's syndrome
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Method
Western Blot
Reference interval
Negative
Result
Results are reported as negative or positive.
Interpretation
Antibodies are markers for sclerodermia and occur in approx. 4-10% of the patients. Can also occur in Raynauds syndrome.
References
- Andraos R et al. Lupus Sci Med. 2022. Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary Sjögren's syndrome and systemic sclerosis. PMID: 36581379
- Didier K et al. RMD Open. 2024. Impact of autoantibody status on stratifying the risk of organ involvement and mortality in SSc: experience from a multicentre French cohort of 1605 patients. PMID: 39572073
Last updated: 2025-12-01
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ENSKILD ANALYS 720
Th/To-antikroppar
Indikation
Misstanke om sklerodermi och differentialdiagnos vid Raynauds fenomen
Provmaterial
Serum
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: rumstemperatur
- Internationellt: kylt
Metod
Westernblot
Referensintervall
Negativt
Resultat
Resultat anges som negativt eller positivt.
Tolkning
Antikroppar är markörer för sklerodermi och förekommer hos ca 4-10% av patienterna. Kan också förekomma vid Raynauds fenomen.
Referenser
- Andraos R et al. Lupus Sci Med. 2022. Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary Sjögren's syndrome and systemic sclerosis. PMID: 36581379
- Didier K et al. RMD Open. 2024. Impact of autoantibody status on stratifying the risk of organ involvement and mortality in SSc: experience from a multicentre French cohort of 1605 patients. PMID: 39572073
Senast uppdaterat: 2025-12-01