INDIVIDUAL TEST 736
Recoverin Antibodies (IgG)
Indication
Suspicion of paraneoplastic retinopathy (Carcinoma Associated Retinopathy, CAR)
Sample material
Serum
- Minim. volume: 0,5 mL
CSF
- Minim. volume: 2,0 mL
Transport
Within Sweden
- room temperature
International
- cold
Method
Immunoblot
Reference interval
Serum
- <5 negative
CSF
- negative
Result
Serum
- results are reported as negative, borderline, or positive with an intensity value.
CSF
- results are reported as negative, borderline, or positive.
Interpretation
Antibodies against recoverin occur almost exclusively in small cell lung cancer with paraneoplastic retinopathy.
References
- Rosenfeld MR, Dalmau J. Neurol Clin. 2018. Paraneoplastic Neurologic Syndromes. PMID: 30072076
- Balint B et al. Brain. 2018. Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology. PMID: 29053777
- Graus F et al. Neurol Neuroimmunol Neuroinflamm. 2021. Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes. PMID: 34006622
- Garza M, Piquet AL. Front Neurol. 2021. Update in Autoimmune Movement Disorders: Newly Described Antigen Targets in Autoimmune and Paraneoplastic Cerebellar Ataxia. PMID: 34489848
Last updated: 2024-10-16
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ENSKILD ANALYS 736
Recoverin-antikroppar (IgG)
Indikation
Misstanke om paraneoplastisk retinopati (carcinoma associated retinopathy, CAR)
Provmaterial
Serum
- Minim. volym: 0,5 mL
Likvor
- Minim. volym: 2,0 mL
Transport
Inom Sverige
- rumstemperatur
Internationellt
- kylt
Metod
Immunoblot
Referensintervall
Serum
- <5 negativt
Likvor
- negativt
Resultat
Serum
- resultat anges som negativt, gränsvärde eller positivt med intensitetsvärde.
Likvor
- resultat anges som negativt, gränsvärde eller positivt.
Tolkning
Recoverin-antikroppar förekommer nästan uteslutande vid paraneoplastisk retinopati associerad med småcellig lungcancer.
Referenser
- Rosenfeld MR, Dalmau J. Neurol Clin. 2018. Paraneoplastic Neurologic Syndromes. PMID: 30072076
- Balint B et al. Brain. 2018. Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology. PMID: 29053777
- Graus F et al. Neurol Neuroimmunol Neuroinflamm. 2021. Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes. PMID: 34006622
- Garza M, Piquet AL. Front Neurol. 2021. Update in Autoimmune Movement Disorders: Newly Described Antigen Targets in Autoimmune and Paraneoplastic Cerebellar Ataxia. PMID: 34489848
Senast uppdaterat: 2024-10-16
Mer information
Detta är en ackrediterad analys.> Läs mer [.pdf]
Mer information om provtagning.
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