DIAGNOSTIC TEST 736

Recoverin Antibodies (IgG)

Diagnostic test for antibodies against Recoverin. For suspicion of paraneoplastic retinopathy (Carcinoma Associated Retinopathy, CAR).

swedac

Accredited. View list of accredited tests [.pdf]

Indication

Suspicion of paraneoplastic retinopathy (Carcinoma Associated Retinopathy, CAR)

Sample material

Serum

  • Minim. volume: 0,5 mL

CSF

  • Minim. volume: 2,0 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Immunoblot

Reference interval

Serum: <6 negative

CSF: negative

Result

Serum: results are reported as negative, borderline, or positive with an intensity value.

CSF: results are reported as negative, borderline, or positive.

Interpretation

Antibodies against recoverin occur almost exclusively in small cell lung cancer with paraneoplastic retinopathy.

References

  • Rosenfeld MR, Dalmau J. Neurol Clin. 2018. Paraneoplastic Neurologic Syndromes. PMID: 30072076
  • Graus F et al. Neurol Neuroimmunol Neuroinflamm. 2021. Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes. PMID: 34006622
  • Guasp M, Dalmau J. Neurology. 2023. Searching for Neuronal Antibodies in Psychiatric Diseases: Uncertain Findings and Implications. PMID: 37353340
  • Kerstens J et al. Neurol Neuroimmunol Neuroinflamm. 2024. Autoimmune Encephalitis and Paraneoplastic Neurologic Syndromes: A Nationwide Study on Epidemiology and Antibody Testing Performance. PMID: 39467237

Included in these panels

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. If you are a new customer, please also include a completed customer information form.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).
    CSF: At least 2 mL CSF (polypropylene tubes).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Last updated: 2026-09-21