INDIVIDUAL TEST 910
C4
Indication
Suspicion of complement activation or other deviations within the complement system
Sample material
EDTA-plasma
- Minim. volume: 0,5 mL
Transport
- Within Sweden: frozen
- International: frozen
Method
Nephelometry
Reference interval
0.13-0.32 g/L
Result
Results are reported as normal, low, or elevated with a concentration (g/L).
Interpretation
An elevated level of C4 can be seen in acute phase reaction. Complementary analyses are often required for the assessment.
References
- Zickert A et al. Rheumatology (Oxford). 2025. Plasma C4d levels correlate with treatment response and renal activity in proliferative lupus nephritis. PMID: 40280868
- Juto A et al. Arthritis Res Ther. 2025. Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation. PMID: 40045390
Last updated: 2025-12-05
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ENSKILD ANALYS 910
C4
Indikation
Misstanke om komplementaktivering eller andra avvikelser inom komplementsystemet
Provmaterial
EDTA-plasma
- Minim. volym: 0,5 mL
Transport
- Inom Sverige: fryst
- Internationellt: fryst
Metod
Nefelometri
Referensintervall
0.13-0.32 g/L
Resultat
Resultat anges som normalt, sänkt eller förhöjt med koncentration (g/L).
Tolkning
Förhöjd nivå C4 kan ses vid akutfasreaktion. Kompletterande analyser krävs ofta för bedömningen.
Referenser
- Zickert A et al. Rheumatology (Oxford). 2025. Plasma C4d levels correlate with treatment response and renal activity in proliferative lupus nephritis. PMID: 40280868
- Juto A et al. Arthritis Res Ther. 2025. Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation. PMID: 40045390
Senast uppdaterat: 2025-12-05