DIAGNOSTIC TEST 910

C4

Diagnostic test for C4. For suspicion of complement activation or other deviations within the complement system.

Indication

Suspicion of complement activation or other deviations within the complement system

Sample material

EDTA-plasma

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: frozen
  • International: frozen

Method

Nephelometry

Reference interval

0.13-0.32 g/L

Result

Results are reported as normal, low, or elevated with a concentration (g/L).

Interpretation

An elevated level of C4 can be seen in acute phase reaction. Complementary analyses are often required for the assessment.

References

  • Zickert A et al. Rheumatology (Oxford). 2025. Plasma C4d levels correlate with treatment response and renal activity in proliferative lupus nephritis. PMID: 40280868
  • Juto A et al. Arthritis Res Ther. 2025. Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation. PMID: 40045390

Included in these panels

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    EDTA Plasma: At least 0.5 mL blood plasma (EDTA tubes).

  3. Send samples and request form

    Within Sweden
    Send samples frozen to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples frozen to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-12-05