DIAGNOSTIC TEST 600
Fibrillarin Antibodies
Diagnostic test for antibodies against fibrillarin. For suspicion of scleroderma.
Indication
Suspicion of scleroderma, differential diagnosis for Raynaud's phenomenon.
Method
Phadia ELIA
Result
The result is expressed as negative, borderline, or positive with a value.
Interpretation
Fibrillarin antibodies occur in about 4% of patients with systemic scleroderma, often together with antibodies against centromeres, RNA-polymerase, and Scl-70. It has also been described in SLE and primary Raynaud's phenomenon. Anti-fibrillarin is more common in patients of African descent than Caucasians. Anti-fibrillarin is more specific for the diffuse form of scleroderma than the limited one.
Included in these panels
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How to order
This test is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-08-18
