DIAGNOSTIC TEST PANEL 584
Primary Membranous Nephropathy (PMN)
Diagnostic test panel for antibodies against THSD7A and PLA2R. For suspicion of primary membranous nephropathy (PMN).
Available as urgent test with results within 24 h.
Indication
Suspicion of primary membranous nephropathy (PMN)
Sample material
Serum
- Minim. volume: 0,5 mL
Transport
- Within Sweden: room temperature
- International: cold
Clinical background
Primary membranous nephropathy (PMN) is an antibody-mediated inflammatory disease of the glomeruli that leads to progressive loss of kidney function.
The inflammation is driven by the production of autoantibodies against the transmembrane protein phospholipase A2 receptor (PLA2R) or Thrombospondin Type 1 Domain Containing 7A (THSD7A), both of which are expressed on the surface of the podocytes in the glomeruli.
Antibodies against PLA2R and THSD7A are strong markers for primary membranous nephropathy (PMN), that forms complement-activating immune complexes deposited on basement membranes in glomeruli with tissue damage and proteinuria as a result. Co-occurrence of antibodies against PLA2R and THSD7A is very rare.
Tests included in panel
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How to order
This test panel is available worldwide for hospitals, clinics, and physicians.
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Print and complete the request form
Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. -
Prepare your samples
Serum: At least 0.5 mL serum (plain serum tubes without additives).
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Send samples and request form
Within Sweden
Samples can be sent at room temperature to:
Envelopes and smaller boxes:
Wieslab AB, Box 50117, 20211 Malmö, Sweden
Larger boxes and frozen samples:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
International
Send samples cold to:
Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden
Last updated: 2025-12-05
