DIAGNOSTIC TEST 990

Tau

Diagnostic test for Tau. For Alzheimer's disease, memory examination, and CNS injury.

Indication

Suspicion of Alzheimer's disease, memory examination or CNS parenchyma injury

Sample material

CSF

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: frozen
  • International: frozen

Method

Chemiluminescence enzyme immunoassay (CELEIA)

Reference interval

< 18 years: < 300 ng/L

18 - <50 years: < 360 ng/L

≥ 50 years: < 409 ng/L

Result

Results are reported as a concentration (ng/L).

Interpretation

Total Tau reflects axonal decomposition. Tau is a structural protein that mostly occurs in cortical unmyelinated axon, where it bind to microtubules with a stabilizing effect. Increased level of total Tau can be seen as a biomarker for Alzheimer's disease, and other neurodegenerative diseases in the central nervous system as well as stroke.

References

  • Dubey D et al. Epilepsy. 2017. Predictive models in the diagnosis and treatment of autoimmune epilepsy. PMID: 28555833
  • Jack CR Jr et al. Alzheimers Dement. 2024. Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup. PMID: 38934362
  • Woyk K et al. J Alzheimers Dis Rep. 2025. The relationship of 18F-FDG-PET to other common biomarkers of dementia in a clinical cohort with memory deficits. PMID: 40290782

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.
  2. Prepare your samples

    CSF: At least 0.5 mL CSF (polypropylene tubes).
  3. Send samples and request form

    Within Sweden
    Send samples frozen to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples frozen to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-12-05