DIAGNOSTIC TEST 720

Th/To Antibodies

Diagnostic test for antibodies against Th/To. For suspicion of scleroderma.

Indication

Suspicion of scleroderma and differential diagnosis of Raynaud's syndrome

Sample material

Serum

  • Minim. volume: 0,5 mL

Transport

  • Within Sweden: room temperature
  • International: cold

Method

Western Blot

Reference interval

Negative

Result

Results are reported as negative or positive.

Interpretation

Antibodies are markers for sclerodermia and occur in approx. 4-10% of the patients. Can also occur in Raynauds syndrome.

References

  • Andraos R et al. Lupus Sci Med. 2022. Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary Sjögren's syndrome and systemic sclerosis. PMID: 36581379
  • Didier K et al. RMD Open. 2024. Impact of autoantibody status on stratifying the risk of organ involvement and mortality in SSc: experience from a multicentre French cohort of 1605 patients. PMID: 39572073

Included in these panels

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How to order

This test is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician.

  2. Prepare your samples

    Serum: At least 0.5 mL serum (plain serum tubes without additives).

  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Read our sampling instructions for more information

Last updated: 2025-12-01