DIAGNOSTIC TEST PANEL 535

Small Fiber Neuropathy (SFN)

Diagnostic test panel for antibodies against FGFR3, TS-HDS, and Plexin D1. For small fiber neuropathy and suspicion of inflammatory sensory neuropathy.

Indication

Suspicion of small fiber neuropathy and inflammatory sensory neuropathy.

Sample material

Serum

  • Minim. volume: 3 tubes x 0,5 mL

Transport

Within Sweden:

  • room temperature

International:

  • cold

Clinical background

Antibodies against Fibroblast Growth Factor (FGFR3) have been reported with sensory neuropathy in patients with autoimmune diseases.

IgM-antibodies against trisulfated heparan disaccharide (TS-HDS) are reported in a subgroup of patients with small fiber neuropathy. TS-HDS IgM-antibodies seem more frequent and specific for small fiber neuropathy than IgG-antibodies against FGFR3.

Antibodies against Plexin D1 can be detected in polyneuropathy patients with sensory polyneuropathy, which is often characterized as burning pain and thermal hyperalgesia.

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How to order

This test panel is available worldwide for hospitals, clinics, and physicians.

  1. Print and complete the request form

    Download the request form. Clearly state the name and phone number of the referring hospital, clinic, or physician. If you are a new customer, please also include a completed customer information form.
  2. Prepare your samples

    Serum: At least 3 tubes x 0.5 mL serum (plain serum tubes without additives).
  3. Send samples and request form

    Within Sweden
    Samples can be sent at room temperature to:
    Envelopes and smaller boxes:
    Wieslab AB, Box 50117, 20211 Malmö, Sweden

    Larger boxes and frozen samples:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

    International
    Send samples cold to:
    Wieslab AB, Lundavägen 151, 21224 Malmö, Sweden

Last updated: 2026-09-30