Review Paper

The Complement System

In this specialist work of writing on the Complement System, Prof. Tom Eirik Mollnes, MD, Ph.D. gives an overview of the complement system, presents primary research, and puts the topic in a clinical and pharma setting.

AUTHOR’S AFFILIATIONS:

Prof. Tom Eirik Mollnes, MD, PhD.
Institute of Immunology, Oslo University Hospital University of Oslo, and Nordland Hospital, Bodø and University of Tromsø, Norway

Review Paper

The Complement System

In this specialist work of writing on the Complement System, Prof. Tom Eirik Mollnes, MD, Ph.D. gives an overview of the complement system, presents primary research, and puts the topic in a clinical and pharma setting.

AUTHOR’S AFFILIATIONS:

Prof. Tom Eirik Mollnes, MD, PhD.
Institute of Immunology, Oslo University Hospital University of Oslo, and Nordland Hospital, Bodø and University of Tromsø, Norway


Contents

  1. The Complement System
    1.1. Structure and molecular function
    1.2. Biological function
  2. Deficiency and dysregulation:
    clinical manifestations
    2.1. Pathophysiology due to deficiencies
    2.2. Pathophysiology due to dysregulation
  3. Complement tests
    3.1. Screening for deficiencies
    3.2. Individual components
    3.3. Activation products
    3.4. Dysregulation and genetics
    3.5. Complement in the therapeutic era
  4. Treatment of samples

 


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Monograph - The Complement System 2